Characterization of an Intrinsically Fluorescent Gonadotropin-Releasing Hormone Receptor and Effects of Ligand Binding on Receptor Lateral Diffusion

Abstract The GnRH receptor (GnRHR) is a G protein-coupled receptor expressed by gonadotropes in the anterior pituitary gland. In the past several years, much has been learned about the structure-function relationships that exist in this receptor with regard to ligand binding and signal transduction....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 1999-02, Vol.140 (2), p.950-957
Hauptverfasser:	Nelson, Scott, Horvat, Regina D., Malvey, Jennifer, Roess, Deborah A., Barisas, B. George, Clay, Colin M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Binding, Competitive Cell fusion Cell Membrane - metabolism CHO Cells COS Cells Cricetinae Diffusion Diffusion rate Fluorescence Fusion protein Gonadotropin-releasing hormone Gonadotropin-Releasing Hormone - analogs & derivatives Gonadotropin-Releasing Hormone - metabolism Gonadotropins Green fluorescent protein Green Fluorescent Proteins Indicators and Reagents Lateral diffusion Ligands Luminescent Proteins - genetics Mammalian cells Membrane fusion Membranes Mice Ovaries Photobleaching Photochemical reactions Pituitary (anterior) Pituitary gland Protein folding Protein structure Proteins Receptor mechanisms Receptors Receptors, LHRH - genetics Receptors, LHRH - metabolism Receptors, LHRH - physiology Recombinant Fusion Proteins - metabolism Recovery Signal transduction Structure-function relationships
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!