Smoking and blood pressure patterns in normotensive pregnant women

This paper examines the relationship between smoking levels and blood pressure patterns of normotensive pregnant women in a prospective cohort of 2193 primiparous and 3176 multiparous, normotensive, Caucasian women selected from the Child Health and Development Studies in Oakland, California, 1959–6...

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Veröffentlicht in:Paediatric and perinatal epidemiology 1999-01, Vol.13 (1), p.22-34
Hauptverfasser: Matkin, C C, Britton, J, Samuels, S, Eskenazi, B
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creator Matkin, C C
Britton, J
Samuels, S
Eskenazi, B
description This paper examines the relationship between smoking levels and blood pressure patterns of normotensive pregnant women in a prospective cohort of 2193 primiparous and 3176 multiparous, normotensive, Caucasian women selected from the Child Health and Development Studies in Oakland, California, 1959–67. Regression lines were fitted to each woman’s blood pressure; mean intercept and slope estimates of the individual regressions were used to create summary profile lines for each smoking dose. Multivariable regression analysis controlled for maternal age, number of visits to the doctor after 20 weeks’ gestation, body mass index and maternal education level. Overall, smokers had lower average diastolic blood pressure (smokers vs. nonsmokers adjusted mean: primiparas, 66.1 vs. 67.2 mmHg; and multiparas, 64.0 vs. 64.7 mmHg) but higher systolic blood pressure (smokers vs. nonsmokers adjusted mean: primiparas, 117.0 vs. 116.0; and multiparas, 112.5 vs. 110.0) than nonsmokers among primiparous and multiparous pregnant women after adjusting for potential confounders. However, these differences are small and there was no clear dose–response relationship between smoking level and blood pressure.
doi_str_mv 10.1046/j.1365-3016.1999.00152.x
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Regression lines were fitted to each woman’s blood pressure; mean intercept and slope estimates of the individual regressions were used to create summary profile lines for each smoking dose. Multivariable regression analysis controlled for maternal age, number of visits to the doctor after 20 weeks’ gestation, body mass index and maternal education level. Overall, smokers had lower average diastolic blood pressure (smokers vs. nonsmokers adjusted mean: primiparas, 66.1 vs. 67.2 mmHg; and multiparas, 64.0 vs. 64.7 mmHg) but higher systolic blood pressure (smokers vs. nonsmokers adjusted mean: primiparas, 117.0 vs. 116.0; and multiparas, 112.5 vs. 110.0) than nonsmokers among primiparous and multiparous pregnant women after adjusting for potential confounders. However, these differences are small and there was no clear dose–response relationship between smoking level and blood pressure.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>9987783</pmid><doi>10.1046/j.1365-3016.1999.00152.x</doi><tpages>13</tpages></addata></record>
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subjects Adult
Blood Pressure - physiology
California - epidemiology
Case-Control Studies
Diastole - physiology
Female
Humans
Least-Squares Analysis
Multivariate Analysis
Pregnancy - physiology
Smoking - epidemiology
Systole - physiology
title Smoking and blood pressure patterns in normotensive pregnant women
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