A Genome-Wide Search Identifies Two Susceptibility Loci for Experimental Autoimmune Encephalomyelitis on Rat Chromosomes 4 and 10

Experimental autoimmune encephalomyelitis (EAE) is an autoimmune disease of the central nervous system that exhibits many pathologic similarities with multiple sclerosis. The genetic loci that contribute to mononuclear cell infiltration of the central nervous system and clinical manifestations of EA...

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Veröffentlicht in:	The Journal of immunology (1950) 1999-02, Vol.162 (4), p.1917-1922
Hauptverfasser:	Roth, Marie-Paule, Viratelle, Carine, Dolbois, Laurence, Delverdier, Maxence, Borot, Nicolas, Pelletier, Lucette, Druet, Philippe, Clanet, Michel, Coppin, Helene
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Chromosome Mapping - methods Crosses, Genetic Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - pathology Genetic Markers Genetic Predisposition to Disease - genetics Genetic Predisposition to Disease - immunology Genome Guinea Pigs Homozygote Phenotype Rats Rats, Inbred BN Rats, Inbred Lew
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