Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses

The steroid hormone estradiol (E2) elicits a spectrum of systemic and uterotropic responses in vivo. For example, E2 treatment of ovariectomized adult and sexually immature rodents leads to uterine leukocytic infiltration, cell proliferation, and organ growth. E2-regulated growth is also associated...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1999-02, Vol.140 (2), p.556-561
Hauptverfasser:	Roper, R J, Griffith, J S, Lyttle, C R, Doerge, R W, McNabb, A W, Broadbent, R E, Teuscher, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosome Mapping Chromosomes, Human, Pair 10 - genetics Chromosomes, Human, Pair 11 - genetics Chromosomes, Human, Pair 5 - genetics Estradiol - physiology Female Genetic Variation - genetics Humans Leukocytes - physiology Mice Mice, Inbred C3H Mice, Inbred C57BL Organ Size - physiology Phenotype Quantitative Trait, Heritable Uterus - anatomy & histology Uterus - cytology Uterus - physiology
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