Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1

The onset of leukaemia caused by type C retroviruses (MLV) in mice is accelerated by the emergence of recombinant polytropic or mink cell focus–forming (MCF) viruses 1 , 2 , 3 , 4 . Susceptibility to infection by polytropic/MCF and also by closely related xenotropic MLV has been mapped to Rmc1 on mo...

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Veröffentlicht in:	Nature genetics 1999-02, Vol.21 (2), p.216-219
Hauptverfasser:	Yang, Yun-Liang, Guo, Lei, Xu, Shuang, Holland, Christine A., Kitamura, Toshio, Hunter, Kent, Cunningham, James M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Agriculture Amino Acid Sequence Animal Genetics and Genomics Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Cell Line Chromosome Mapping Cricetinae Fundamental and applied biological sciences. Psychology Gene Function Genes. Genome Human Genetics Humans letter Leukemia Virus, Murine - genetics Leukemia Virus, Murine - metabolism Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mink cell focus-forming virus Mink Cell Focus-Inducing Viruses - genetics Mink Cell Focus-Inducing Viruses - metabolism Molecular and cellular biology Molecular genetics Molecular Sequence Data Murine leukemia virus Oocytes - cytology Receptors, G-Protein-Coupled Receptors, Virus - genetics Receptors, Virus - metabolism Transfection Xenopus laevis
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