Primary Pulmonary Melanoma: Case Report and Literature Review
Primary pulmonary melanoma is a very rare disease, with only 19 cases previously reported in the English language literature. These cases suggest that melanoma can arise in the lung as a primary tumor, probably from residual melanoblasts. Primary pulmonary melanoma is frequently endobronchial and of...
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Veröffentlicht in: | Mayo Clinic proceedings 1999, Vol.74 (1), p.62-66 |
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description | Primary pulmonary melanoma is a very rare disease, with only 19 cases previously reported in the English language literature. These cases suggest that melanoma can arise in the lung as a primary tumor, probably from residual melanoblasts. Primary pulmonary melanoma is frequently endobronchial and often manifests with symptoms of cough, hemoptysis, and lobar collapse. Aggressive surgical resection, irrespective of lymph node involvement, offers possible long-term survival in some patients. The diagnosis of primary pulmonary melanoma necessitates that both clinical and histologic criteria be fulfilled. Herein diagnostic criteria are proposed, and the diagnostic approach is discussed. |
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These cases suggest that melanoma can arise in the lung as a primary tumor, probably from residual melanoblasts. Primary pulmonary melanoma is frequently endobronchial and often manifests with symptoms of cough, hemoptysis, and lobar collapse. Aggressive surgical resection, irrespective of lymph node involvement, offers possible long-term survival in some patients. The diagnosis of primary pulmonary melanoma necessitates that both clinical and histologic criteria be fulfilled. 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These cases suggest that melanoma can arise in the lung as a primary tumor, probably from residual melanoblasts. Primary pulmonary melanoma is frequently endobronchial and often manifests with symptoms of cough, hemoptysis, and lobar collapse. Aggressive surgical resection, irrespective of lymph node involvement, offers possible long-term survival in some patients. The diagnosis of primary pulmonary melanoma necessitates that both clinical and histologic criteria be fulfilled. Herein diagnostic criteria are proposed, and the diagnostic approach is discussed.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Autopsy</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Lung Neoplasms - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanoma - diagnosis</subject><subject>Melanoma - pathology</subject><subject>Pneumology</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0025-6196</issn><issn>1942-5546</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><recordid>eNplkFtrGzEQRkVJcRyn9BcEllCSp3VHWl2sQB-KyQ0cakL7LFRpBBv24kq7Dfn3lfGSQPM0w8zhm-EQ8pnCkoMUXxVf0qVkH8icas5KIbg8InMAJkpJtTwmJyk9AYDSms_ITOuVEpWYk2_bWLc2vhTbsWn7bt89YGO7vrVXxdomLB5x18ehsJ0vNvWA0Q5j3E__1vh8Sj4G2yT8NNUF-XVz_XN9V25-3N6vv29KxzkMZaUFOKASUEgng0NEBZz5AFoxXQWwNni94j7TVApgTjvpPUcWhHAsVAtyccjdxf7PiGkwbZ0cNvlR7MdkpBaKAsgMnv8HPvVj7PJvhlG5UpXgPEOXB8jFPqWIwewOEgwFs7dpFDfUSJbJsylu_N2if-UmfXn_Zdrb5GwTou1cnd7ipGCq2sfQA4bZUfYWTXI1dg59HdENxvf1u9P_ADxRikA</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>Ost, David</creator><creator>Joseph, Carmel</creator><creator>Sogoloff, Helen</creator><creator>Menezes, Geetha</creator><general>Elsevier Inc</general><general>Mayo Medical Ventures</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4U-</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>1999</creationdate><title>Primary Pulmonary Melanoma: Case Report and Literature Review</title><author>Ost, David ; 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These cases suggest that melanoma can arise in the lung as a primary tumor, probably from residual melanoblasts. Primary pulmonary melanoma is frequently endobronchial and often manifests with symptoms of cough, hemoptysis, and lobar collapse. Aggressive surgical resection, irrespective of lymph node involvement, offers possible long-term survival in some patients. The diagnosis of primary pulmonary melanoma necessitates that both clinical and histologic criteria be fulfilled. Herein diagnostic criteria are proposed, and the diagnostic approach is discussed.</abstract><cop>Rochester, MN</cop><pub>Elsevier Inc</pub><pmid>9987535</pmid><doi>10.4065/74.1.62</doi><tpages>5</tpages></addata></record> |
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subjects | Aged Aged, 80 and over Autopsy Biological and medical sciences Diagnosis, Differential Humans Lung Neoplasms - diagnosis Lung Neoplasms - pathology Male Medical sciences Melanoma - diagnosis Melanoma - pathology Pneumology Tumors of the respiratory system and mediastinum |
title | Primary Pulmonary Melanoma: Case Report and Literature Review |
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