Differences in Treadmill Exercise Tolerance Parameters Between Patients With Partial and Advanced Interatrial Depolarization Abnormality

Advanced interatrial block (aIAB) is considerably much less common than partial interatrial block (pIAB), occuring in

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Veröffentlicht in:The American journal of cardiology 2008-10, Vol.102 (7), p.866-870
Hauptverfasser: Raja, Asim, MD, Ariyarajah, Vignendra, MD, Fernandes, Jaxon, MD, Apiyasawat, Sirin, MD, Khadem, Aliasghar, MD, Barac, Ivan, MD, Spodick, David H., MD, DSc
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container_title The American journal of cardiology
container_volume 102
creator Raja, Asim, MD
Ariyarajah, Vignendra, MD
Fernandes, Jaxon, MD
Apiyasawat, Sirin, MD
Khadem, Aliasghar, MD
Barac, Ivan, MD
Spodick, David H., MD, DSc
description Advanced interatrial block (aIAB) is considerably much less common than partial interatrial block (pIAB), occuring in
doi_str_mv 10.1016/j.amjcard.2008.05.026
format Article
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Less is, therefore, known of the true clinical burden of aIAB, particularly in relation to graded exercise. Therefore, 12 patients with aIAB and 30 patients with pIAB who performed a baseline exercise tolerance test and had a repeat test performed ≥2 years later were included in the study. Exercise tolerance, echocardiographic findings, and major adverse cardiovascular events were compared. Left atrial size progressed at a significantly faster rate in those with aIAB. In addition, Duke Prognostic Treadmill scores were significantly lower on follow-up in those patients with aIAB. Overall, patients with aIAB had significantly greater left atrial size (48.3 ± 9 vs 42.8 ± 4 mm, p &lt;0.01) and significantly lower Duke Prognostic Treadmill scores than those with pIAB (−0.2 ± 5 vs 4.1 ± 4, p &lt;0.05). There were, however, no significant differences in the occurence of major adverse cardiovascular events. In conclusion, left atrial size progressed at a significantly faster rate but Duke Prognostic Treadmill scores were significantly lower in those with aIAB compared with patients with pIAB after ≥2 years of follow-up. Further study is required to determine whether patients with aIAB require follow-up echocardiography and/or exercise tolerance tests for optimal risk stratification.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2008.05.026</identifier><identifier>PMID: 18805112</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Cardiovascular disease ; Echocardiography ; Electrocardiography ; Exercise ; Exercise Test ; Exercise Tolerance ; Female ; Heart ; Heart Atria - physiopathology ; Heart Block - diagnostic imaging ; Heart Block - physiopathology ; Humans ; Male ; Medical prognosis ; Medical sciences ; Studies</subject><ispartof>The American journal of cardiology, 2008-10, Vol.102 (7), p.866-870</ispartof><rights>Elsevier Inc.</rights><rights>2008 Elsevier Inc.</rights><rights>2008 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. 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Less is, therefore, known of the true clinical burden of aIAB, particularly in relation to graded exercise. Therefore, 12 patients with aIAB and 30 patients with pIAB who performed a baseline exercise tolerance test and had a repeat test performed ≥2 years later were included in the study. Exercise tolerance, echocardiographic findings, and major adverse cardiovascular events were compared. Left atrial size progressed at a significantly faster rate in those with aIAB. In addition, Duke Prognostic Treadmill scores were significantly lower on follow-up in those patients with aIAB. Overall, patients with aIAB had significantly greater left atrial size (48.3 ± 9 vs 42.8 ± 4 mm, p &lt;0.01) and significantly lower Duke Prognostic Treadmill scores than those with pIAB (−0.2 ± 5 vs 4.1 ± 4, p &lt;0.05). There were, however, no significant differences in the occurence of major adverse cardiovascular events. In conclusion, left atrial size progressed at a significantly faster rate but Duke Prognostic Treadmill scores were significantly lower in those with aIAB compared with patients with pIAB after ≥2 years of follow-up. Further study is required to determine whether patients with aIAB require follow-up echocardiography and/or exercise tolerance tests for optimal risk stratification.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. 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In conclusion, left atrial size progressed at a significantly faster rate but Duke Prognostic Treadmill scores were significantly lower in those with aIAB compared with patients with pIAB after ≥2 years of follow-up. Further study is required to determine whether patients with aIAB require follow-up echocardiography and/or exercise tolerance tests for optimal risk stratification.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18805112</pmid><doi>10.1016/j.amjcard.2008.05.026</doi><tpages>5</tpages></addata></record>
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subjects Aged
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Echocardiography
Electrocardiography
Exercise
Exercise Test
Exercise Tolerance
Female
Heart
Heart Atria - physiopathology
Heart Block - diagnostic imaging
Heart Block - physiopathology
Humans
Male
Medical prognosis
Medical sciences
Studies
title Differences in Treadmill Exercise Tolerance Parameters Between Patients With Partial and Advanced Interatrial Depolarization Abnormality
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