Process control in a high shear mixer‐granulator using wet mass consistency: The effect of formulation variables

This work investigates the relationships between the wet mass consistency/viscosity of samples prepared in a mixer‐granulator and physical properties of the dry granules produced from the wet mass; namely, size distribution, bulk density (Hausner ratio), friability, and flow avalanching behavior. Th...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1999-02, Vol.88 (2), p.191-195
Hauptverfasser:	Faure, Anne, Grimsey, Ian M., Rowe, Ray C., York, Peter, Cliff, Mike J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Drug Compounding - instrumentation General pharmacology Medical sciences Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Powders Regression Analysis Rheology Tablets
Online-Zugang:	Volltext
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