Heterogeneity of clonal development in chronic myeloproliferative disorders

Recent reports have suggested a previously unexpected variability in the expression of the dominant neoplastic clone in myeloproliferative disorders (MPD). We evaluated 49 female patients with MPD and informative at the X‐linked androgen receptor (AR) locus to establish the X chromosome inactivation...

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Veröffentlicht in:	American journal of hematology 1999-02, Vol.60 (2), p.158-160
Hauptverfasser:	Ferraris, Anna Maria, Mangerini, Rosa, Racchi, Omar, Rapezzi, Davide, Rolfo, Michela, Casciaro, Salvatore, Gaetani, Gian Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over B-Lymphocytes - pathology Biological and medical sciences clonality Clone Cells - pathology Dosage Compensation, Genetic Female Hematologic and hematopoietic diseases Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Middle Aged myeloproliferative Myeloproliferative Disorders - genetics Myeloproliferative Disorders - pathology Neutrophils - pathology Polymerase Chain Reaction Receptors, Androgen - genetics T-Lymphocytes - pathology X inactivation
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