Hematopoietic Stem-Cell Transplantation for the Treatment of Severe Combined Immunodeficiency

Severe combined immunodeficiency is a rare, fatal syndrome that can be due to a variety of genetic abnormalities causing profound deficiencies of lymphocytes. 1 – 4 Shortly after the discovery of the HLA system in 1968, 5 , 6 immune function was corrected in an infant with severe combined immunodefi...

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Veröffentlicht in:	The New England journal of medicine 1999-02, Vol.340 (7), p.508-516
Hauptverfasser:	Buckley, Rebecca H, Schiff, Sherrie E, Schiff, Richard I, Markert, M. Louise, Williams, Larry W, Roberts, Joseph L, Myers, Laurie A, Ward, Frances E
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - physiology Biological and medical sciences Bone marrow Family medical history Female Graft vs Host Disease Hematopoietic Stem Cell Transplantation Histocompatibility Testing Humans Immune system Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infant Infant, Newborn Killer Cells, Natural - physiology Lymphocyte Depletion Lymphocytes Male Medical sciences Mutation Phenotype Prospective Studies Severe Combined Immunodeficiency - genetics Severe Combined Immunodeficiency - immunology Severe Combined Immunodeficiency - therapy Studies Survival Analysis T-Lymphocytes - immunology T-Lymphocytes - physiology Transplants & implants
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