Serum antithyroid antibodies in female patients with chronic urticaria
To determine the frequencies of serum antithyroglobulin and antimicrosomal autoantibodies in female patients with chronic urticaria, and the association between thyroid autoantibodies and chronic urticaria, if any. Non-interventional, case-control analytic study. This study was carried out by the De...
Gespeichert in:
| Veröffentlicht in: | Journal of the College of Physicians and Surgeons--Pakistan 2008-08, Vol.18 (8), p.498-501 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 501 |
|---|---|
| container_issue | 8 |
| container_start_page | 498 |
| container_title | Journal of the College of Physicians and Surgeons--Pakistan |
| container_volume | 18 |
| creator | Aamir, Iram Siddiqa Tauheed, Shoaib Majeed, Farrukh Atif, Alina |
| description | To determine the frequencies of serum antithyroglobulin and antimicrosomal autoantibodies in female patients with chronic urticaria, and the association between thyroid autoantibodies and chronic urticaria, if any.
Non-interventional, case-control analytic study.
This study was carried out by the Department of Physiology, Dow University of Health Sciences, Karachi, from December 2004 to January 2006 on patients selected from Department of Dermatology and Medical Units of Civil Hospital, Jinnah Postgraduate Medical Centre and The Aga Khan University Hospital, Karachi and from the Community Clinics in Karachi.
A total number of 90 subjects were enrolled and divided in three groups consisting of 30 patients each. Group 1 comprised of patients with diagnosis of chronic urticaria, Group 2 of diagnosed cases of hypothyroidism with/without urticaria, and Group 3 of normal age and gender-matched healthy volunteers. In all patients, serum antithyroid autoantibodies (antithyroglobulin and antimicrosomal) and thyroid profile (serum T3, T4 and TSH levels) was carried out. Chi-square test was used to determine significance of proportion of variables at p < 0.05.
Elevated titres of antithyroglobulin antibodies were found to be present in 9 (30%) patients in Group 1 (chronic urticaria), 24 (80%) patients in Group 2 (known cases of hypothyroidism) compared to control. Elevated titres of antimicrosomal antibodies were found to be present in 13 (43.3%) patients in Group 1, 27 (90%) patients in Group 2 (known cases of hypothyroidism) compared to control. The association between hypothyroidism and chronic urticaria with regard to autoantibodies titres was highly significance (p |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_69562139</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69562139</sourcerecordid><originalsourceid>FETCH-LOGICAL-p209t-af7d364639dcd2551635ecbb2d9ef3a7b1e196b1af63c2dc398bdaae5ed5141b3</originalsourceid><addsrcrecordid>eNo1z8FLwzAYBfAcFDen_4Lk5K3QJEuaHGU4FQYeVPBWviRfWaRpa5Ii--8dup3eO_x48C7IktWcV0KrzwW5zvmrroVkWl-RBdON0VKrJdm-YZojhaGEsj-kMfi_bkcfMNMw0A4j9EgnKAGHkunP0VG3T-MQHJ1TCQ5SgBty2UGf8faUK_KxfXzfPFe716eXzcOumnhtSgVd44VaK2G881xKpoREZy33BjsBjWXIjLIMOiUc904YbT0ASvSSrZkVK3L_vzul8XvGXNoYssO-hwHHObfKSMWZMEd4d4KzjejbKYUI6dCen4tfFoZV0w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69562139</pqid></control><display><type>article</type><title>Serum antithyroid antibodies in female patients with chronic urticaria</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Aamir, Iram Siddiqa ; Tauheed, Shoaib ; Majeed, Farrukh ; Atif, Alina</creator><creatorcontrib>Aamir, Iram Siddiqa ; Tauheed, Shoaib ; Majeed, Farrukh ; Atif, Alina</creatorcontrib><description>To determine the frequencies of serum antithyroglobulin and antimicrosomal autoantibodies in female patients with chronic urticaria, and the association between thyroid autoantibodies and chronic urticaria, if any.
Non-interventional, case-control analytic study.
This study was carried out by the Department of Physiology, Dow University of Health Sciences, Karachi, from December 2004 to January 2006 on patients selected from Department of Dermatology and Medical Units of Civil Hospital, Jinnah Postgraduate Medical Centre and The Aga Khan University Hospital, Karachi and from the Community Clinics in Karachi.
A total number of 90 subjects were enrolled and divided in three groups consisting of 30 patients each. Group 1 comprised of patients with diagnosis of chronic urticaria, Group 2 of diagnosed cases of hypothyroidism with/without urticaria, and Group 3 of normal age and gender-matched healthy volunteers. In all patients, serum antithyroid autoantibodies (antithyroglobulin and antimicrosomal) and thyroid profile (serum T3, T4 and TSH levels) was carried out. Chi-square test was used to determine significance of proportion of variables at p < 0.05.
Elevated titres of antithyroglobulin antibodies were found to be present in 9 (30%) patients in Group 1 (chronic urticaria), 24 (80%) patients in Group 2 (known cases of hypothyroidism) compared to control. Elevated titres of antimicrosomal antibodies were found to be present in 13 (43.3%) patients in Group 1, 27 (90%) patients in Group 2 (known cases of hypothyroidism) compared to control. The association between hypothyroidism and chronic urticaria with regard to autoantibodies titres was highly significance (p <0.001).
A highly statistically significant association was found between chronic urticaria and hypothyroidism with special regard to antithyroglobulin and antimicrosomal autoantibodies. Therefore, assays of these two autoantibodies are justified for the early diagnosis of autoimmune thyroiditis in combination with chronic urticaria for better treatment options.</description><identifier>ISSN: 1022-386X</identifier><identifier>PMID: 18798586</identifier><language>eng</language><publisher>Pakistan</publisher><subject>Adult ; Autoantibodies - blood ; Autoantibodies - immunology ; Autoimmunity - immunology ; Case-Control Studies ; Chronic Disease ; Female ; Humans ; Middle Aged ; Risk Factors ; Thyroid Diseases - blood ; Thyroid Diseases - immunology ; Thyroiditis, Autoimmune - blood ; Thyroiditis, Autoimmune - immunology ; Urticaria - blood ; Urticaria - immunology ; Urticaria - physiopathology</subject><ispartof>Journal of the College of Physicians and Surgeons--Pakistan, 2008-08, Vol.18 (8), p.498-501</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18798586$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aamir, Iram Siddiqa</creatorcontrib><creatorcontrib>Tauheed, Shoaib</creatorcontrib><creatorcontrib>Majeed, Farrukh</creatorcontrib><creatorcontrib>Atif, Alina</creatorcontrib><title>Serum antithyroid antibodies in female patients with chronic urticaria</title><title>Journal of the College of Physicians and Surgeons--Pakistan</title><addtitle>J Coll Physicians Surg Pak</addtitle><description>To determine the frequencies of serum antithyroglobulin and antimicrosomal autoantibodies in female patients with chronic urticaria, and the association between thyroid autoantibodies and chronic urticaria, if any.
Non-interventional, case-control analytic study.
This study was carried out by the Department of Physiology, Dow University of Health Sciences, Karachi, from December 2004 to January 2006 on patients selected from Department of Dermatology and Medical Units of Civil Hospital, Jinnah Postgraduate Medical Centre and The Aga Khan University Hospital, Karachi and from the Community Clinics in Karachi.
A total number of 90 subjects were enrolled and divided in three groups consisting of 30 patients each. Group 1 comprised of patients with diagnosis of chronic urticaria, Group 2 of diagnosed cases of hypothyroidism with/without urticaria, and Group 3 of normal age and gender-matched healthy volunteers. In all patients, serum antithyroid autoantibodies (antithyroglobulin and antimicrosomal) and thyroid profile (serum T3, T4 and TSH levels) was carried out. Chi-square test was used to determine significance of proportion of variables at p < 0.05.
Elevated titres of antithyroglobulin antibodies were found to be present in 9 (30%) patients in Group 1 (chronic urticaria), 24 (80%) patients in Group 2 (known cases of hypothyroidism) compared to control. Elevated titres of antimicrosomal antibodies were found to be present in 13 (43.3%) patients in Group 1, 27 (90%) patients in Group 2 (known cases of hypothyroidism) compared to control. The association between hypothyroidism and chronic urticaria with regard to autoantibodies titres was highly significance (p <0.001).
A highly statistically significant association was found between chronic urticaria and hypothyroidism with special regard to antithyroglobulin and antimicrosomal autoantibodies. Therefore, assays of these two autoantibodies are justified for the early diagnosis of autoimmune thyroiditis in combination with chronic urticaria for better treatment options.</description><subject>Adult</subject><subject>Autoantibodies - blood</subject><subject>Autoantibodies - immunology</subject><subject>Autoimmunity - immunology</subject><subject>Case-Control Studies</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Risk Factors</subject><subject>Thyroid Diseases - blood</subject><subject>Thyroid Diseases - immunology</subject><subject>Thyroiditis, Autoimmune - blood</subject><subject>Thyroiditis, Autoimmune - immunology</subject><subject>Urticaria - blood</subject><subject>Urticaria - immunology</subject><subject>Urticaria - physiopathology</subject><issn>1022-386X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z8FLwzAYBfAcFDen_4Lk5K3QJEuaHGU4FQYeVPBWviRfWaRpa5Ii--8dup3eO_x48C7IktWcV0KrzwW5zvmrroVkWl-RBdON0VKrJdm-YZojhaGEsj-kMfi_bkcfMNMw0A4j9EgnKAGHkunP0VG3T-MQHJ1TCQ5SgBty2UGf8faUK_KxfXzfPFe716eXzcOumnhtSgVd44VaK2G881xKpoREZy33BjsBjWXIjLIMOiUc904YbT0ASvSSrZkVK3L_vzul8XvGXNoYssO-hwHHObfKSMWZMEd4d4KzjejbKYUI6dCen4tfFoZV0w</recordid><startdate>200808</startdate><enddate>200808</enddate><creator>Aamir, Iram Siddiqa</creator><creator>Tauheed, Shoaib</creator><creator>Majeed, Farrukh</creator><creator>Atif, Alina</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200808</creationdate><title>Serum antithyroid antibodies in female patients with chronic urticaria</title><author>Aamir, Iram Siddiqa ; Tauheed, Shoaib ; Majeed, Farrukh ; Atif, Alina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-af7d364639dcd2551635ecbb2d9ef3a7b1e196b1af63c2dc398bdaae5ed5141b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Autoantibodies - blood</topic><topic>Autoantibodies - immunology</topic><topic>Autoimmunity - immunology</topic><topic>Case-Control Studies</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Thyroid Diseases - blood</topic><topic>Thyroid Diseases - immunology</topic><topic>Thyroiditis, Autoimmune - blood</topic><topic>Thyroiditis, Autoimmune - immunology</topic><topic>Urticaria - blood</topic><topic>Urticaria - immunology</topic><topic>Urticaria - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aamir, Iram Siddiqa</creatorcontrib><creatorcontrib>Tauheed, Shoaib</creatorcontrib><creatorcontrib>Majeed, Farrukh</creatorcontrib><creatorcontrib>Atif, Alina</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the College of Physicians and Surgeons--Pakistan</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aamir, Iram Siddiqa</au><au>Tauheed, Shoaib</au><au>Majeed, Farrukh</au><au>Atif, Alina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum antithyroid antibodies in female patients with chronic urticaria</atitle><jtitle>Journal of the College of Physicians and Surgeons--Pakistan</jtitle><addtitle>J Coll Physicians Surg Pak</addtitle><date>2008-08</date><risdate>2008</risdate><volume>18</volume><issue>8</issue><spage>498</spage><epage>501</epage><pages>498-501</pages><issn>1022-386X</issn><abstract>To determine the frequencies of serum antithyroglobulin and antimicrosomal autoantibodies in female patients with chronic urticaria, and the association between thyroid autoantibodies and chronic urticaria, if any.
Non-interventional, case-control analytic study.
This study was carried out by the Department of Physiology, Dow University of Health Sciences, Karachi, from December 2004 to January 2006 on patients selected from Department of Dermatology and Medical Units of Civil Hospital, Jinnah Postgraduate Medical Centre and The Aga Khan University Hospital, Karachi and from the Community Clinics in Karachi.
A total number of 90 subjects were enrolled and divided in three groups consisting of 30 patients each. Group 1 comprised of patients with diagnosis of chronic urticaria, Group 2 of diagnosed cases of hypothyroidism with/without urticaria, and Group 3 of normal age and gender-matched healthy volunteers. In all patients, serum antithyroid autoantibodies (antithyroglobulin and antimicrosomal) and thyroid profile (serum T3, T4 and TSH levels) was carried out. Chi-square test was used to determine significance of proportion of variables at p < 0.05.
Elevated titres of antithyroglobulin antibodies were found to be present in 9 (30%) patients in Group 1 (chronic urticaria), 24 (80%) patients in Group 2 (known cases of hypothyroidism) compared to control. Elevated titres of antimicrosomal antibodies were found to be present in 13 (43.3%) patients in Group 1, 27 (90%) patients in Group 2 (known cases of hypothyroidism) compared to control. The association between hypothyroidism and chronic urticaria with regard to autoantibodies titres was highly significance (p <0.001).
A highly statistically significant association was found between chronic urticaria and hypothyroidism with special regard to antithyroglobulin and antimicrosomal autoantibodies. Therefore, assays of these two autoantibodies are justified for the early diagnosis of autoimmune thyroiditis in combination with chronic urticaria for better treatment options.</abstract><cop>Pakistan</cop><pmid>18798586</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1022-386X |
| ispartof | Journal of the College of Physicians and Surgeons--Pakistan, 2008-08, Vol.18 (8), p.498-501 |
| issn | 1022-386X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69562139 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Autoantibodies - blood Autoantibodies - immunology Autoimmunity - immunology Case-Control Studies Chronic Disease Female Humans Middle Aged Risk Factors Thyroid Diseases - blood Thyroid Diseases - immunology Thyroiditis, Autoimmune - blood Thyroiditis, Autoimmune - immunology Urticaria - blood Urticaria - immunology Urticaria - physiopathology |
| title | Serum antithyroid antibodies in female patients with chronic urticaria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T16%3A14%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Serum%20antithyroid%20antibodies%20in%20female%20patients%20with%20chronic%20urticaria&rft.jtitle=Journal%20of%20the%20College%20of%20Physicians%20and%20Surgeons--Pakistan&rft.au=Aamir,%20Iram%20Siddiqa&rft.date=2008-08&rft.volume=18&rft.issue=8&rft.spage=498&rft.epage=501&rft.pages=498-501&rft.issn=1022-386X&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E69562139%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69562139&rft_id=info:pmid/18798586&rfr_iscdi=true |