A liposomal model that mimics the cutaneous production of vitamin D3. Studies of the mechanism of the membrane-enhanced thermal isomerization of previtamin D3 to vitamin D3

We reported previously that the rate of previtamin D3 (preD3) vitamin D3 isomerization was enhanced by about 10 times in the skin compared with that in organic solvents. To elucidate the mechanism by which the rate of this reaction is enhanced in the skin, we developed a liposomal model that mimick...

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Veröffentlicht in:	The Journal of biological chemistry 1999-02, Vol.274 (7), p.4174-4179
Hauptverfasser:	Tian, X. Q., Holick, M. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dipalmitoylphosphatidylcholine Cholecalciferol - analogs & derivatives Cholecalciferol - biosynthesis Cholecalciferol - metabolism Chromatography, High Pressure Liquid Hot Temperature Humans In Vitro Techniques Isomerism Life Sciences (General) Liposomes Models, Biological Photolysis Skin - metabolism Space life sciences
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