Distinct actions of interleukin-9 and interleukin-4 on a hematopoietic stem cell line, EMLC1

EMLC1 is a hematopoietic stem cell line that depends on stem cell factor (SCF) for growth and generates lymphoid, erythroid and myeloid progenitors in the presence of different cytokines. We have studied signaling events leading to cell proliferation and differentiation of EMLC1 mediated by interleu...

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Veröffentlicht in:	Experimental hematology 1999, Vol.27 (1), p.139-146
Hauptverfasser:	Wang, Xin-Yuan, Gelfanov, Vasily, Sun, Hui Bin, Tsai, Schickwann, Yang, Yu-Chung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - drug effects Cell Division - drug effects Cell Line - chemistry Erythroid Precursor Cells - cytology Erythroid Precursor Cells - drug effects Gene Expression - drug effects Genes, myc - genetics Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - drug effects Hematopoietic Stem Cells - physiology Immunoblotting Interleukin-4 - pharmacology Interleukin-4 - physiology Interleukin-9 - pharmacology Interleukin-9 - physiology Mice Phosphorylation - drug effects Protein-Tyrosine Kinases - metabolism Stem cell—IL-4—IL-9
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