Evolution of thyroid hormone binding by transthyretins in birds and mammals

Transthyretin, a protein synthesized and secreted by the choroid plexus and liver, binds thyroid hormones in extracellular compartments. This binding prevents accumulation of thyroid hormones in the lipids of membranes, establishing extracellular thyroid hormone pools for the distribution of the hor...

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Veröffentlicht in:	European journal of biochemistry 1999-01, Vol.259 (1/2), p.534-542
Hauptverfasser:	Chang, L, Munro, S.L.A, Richardson, S.J, Schreiber, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence animal physiology Animals binding Biological Sciences Birds evolution Evolution, Molecular Humans Mammals Marsupialia Molecular Sequence Data Prealbumin - chemistry Prealbumin - metabolism Protein Conformation Rats Sequence Analysis Sequence Homology, Amino Acid Thyroid Hormones - metabolism thyroxine Thyroxine - metabolism transthyretin triiodothyronine Triiodothyronine - metabolism
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