A Comparison of C3a and C5a-Mediated Stable Adhesion of Rolling Eosinophils in Postcapillary Venules and Transendothelial Migration In Vitro and In Vivo

The comparative ability of the complement anaphylatoxins C3a and C5a to mediate leukocyte adhesion and transendothelial migration in vivo and in vitro was investigated. Superfusion of IL-1beta-stimulated rabbit mesentery with C3a resulted in a rapid and stable adhesion of rolling eosinophils, but no...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1999-01, Vol.162 (2), p.1127-1136
Hauptverfasser:	DiScipio, Richard G, Daffern, Pamela J, Jagels, Mark A, Broide, David H, Sriramarao, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology CD18 Antigens - immunology Cell Adhesion - immunology Cell Adhesion Molecules - biosynthesis Cell Movement - drug effects Cell Movement - immunology Complement C3a - administration & dosage Complement C3a - physiology Complement C5a - administration & dosage Complement C5a - physiology Endothelium, Vascular - cytology Endothelium, Vascular - immunology Eosinophils - immunology Hemodynamics Humans Infusion Pumps Integrin alpha4beta1 Integrins - immunology Interleukin-1 - pharmacology Lysine Carboxypeptidase - pharmacology Mesentery - blood supply Neutrophils - immunology Rabbits Receptors, Lymphocyte Homing - immunology Venules - cytology Venules - immunology Venules - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!