WNT5A Expression Increases during Melanoma Progression and Correlates with Outcome

Purpose: Wnt ligands play a major role in development and are important in cancer. Expression microarray analysis correlates one member of this family, WNT5A, to a subclass of melanomas with increased motility and invasion. There are no large studies of clinical samples primarily addressing the impo...

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Veröffentlicht in:	Clinical cancer research 2008-09, Vol.14 (18), p.5825-5832
Hauptverfasser:	DA FORNO, Philip D, PRINGLE, J. Howard, HUTCHINSON, Peter, OSBORN, Joy, QIANG HUANG, POTTER, Linda, HANCOX, Rachael A, FLETCHER, Alan, SALDANHA, Gerald S
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cell Line, Tumor Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cytoplasm - metabolism Dermatology Disease Progression Female Humans Male Medical sciences melanoma Melanoma - metabolism Melanoma - pathology metastasis Middle Aged Neoplasm Metastasis Pharmacology. Drug treatments Prognosis progression Proto-Oncogene Proteins - metabolism Skin Neoplasms - metabolism Skin Neoplasms - pathology survival Survival Analysis Tumors of the skin and soft tissue. Premalignant lesions Wnt Proteins - metabolism Wnt-5a Protein WNT5A
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