Hepatitis C virus core protein enhances NF-kappaB signal pathway triggering by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha

Our previous study indicated that the core protein of hepatitis C virus (HCV) can associate with tumor necrosis factor receptor (TNFR)-related lymphotoxin-beta receptor (LT-betaR) and that this protein-protein interaction plays a modulatory effect on the cytolytic activity of recombinant form LT-bet...

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Veröffentlicht in:	Journal of virology 1999-02, Vol.73 (2), p.1672-1681
Hauptverfasser:	You, L R, Chen, C M, Lee, Y H
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell Nucleus - metabolism DNA-Binding Proteins - metabolism HeLa Cells Humans I-kappa B Proteins JNK Mitogen-Activated Protein Kinases Ligands Lymphotoxin beta Receptor Lymphotoxin-alpha - metabolism Lymphotoxin-beta Membrane Proteins - metabolism Mitogen-Activated Protein Kinases NF-kappa B - metabolism NF-KappaB Inhibitor alpha Oligodeoxyribonucleotides - metabolism Receptors, Tumor Necrosis Factor - metabolism Signal Transduction Transcription, Genetic Tumor Cells, Cultured Tumor Necrosis Factor-alpha - metabolism Tumor Necrosis Factor-alpha - pharmacology Viral Core Proteins - metabolism
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