Effects of ultrasound-assisted compaction on Ketoprofen/Eudragit® S100 Mixtures

Ketoprofen alone and in binary mixtures with Eudragit® S100 was compacted by an ultrasound-assisted (US) tableting machine at an energy ranging from 50 to 400 J. The final material was analysed by TLC and HPLC: no decomposition product of the active agent was found. IR spectra and HSM revealed the a...

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Veröffentlicht in:	European journal of pharmaceutical sciences 1999-02, Vol.7 (3), p.207-213
Hauptverfasser:	Sancin, Pietro, Caputo, Otto, Cavallari, Cristina, Passerini, Nadia, Rodriguez, Lorenzo, Cini, Maurizio, Fini, Adamo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - chemistry Amorphous state Anti-Inflammatory Agents, Non-Steroidal - chemistry Biological and medical sciences Differential thermal analysis Drug Compounding Eudragit® S100 Excipients - chemistry General pharmacology Ketoprofen Ketoprofen - chemistry Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymethacrylic Acids Tablets Ultrasonics Ultrasound compaction
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