Reversal of Subchronic PCP-Induced Deficits in Attentional Set Shifting in Rats by Sertindole and a 5-HT6 Receptor Antagonist: Comparison Among Antipsychotics

Currently accepted treatments for schizophrenia can effectively control positive symptoms but have limited impact on cognitive deficits in schizophrenia. The purpose of these experiments was to address this unmet need by characterizing the effects of classical and second-generation antipsychotics on...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2008-10, Vol.33 (11), p.2657-2666
Hauptverfasser:	Rodefer, Joshua S, Nguyen, Tuyet N, Karlsson, Jens-Jakob, Arnt, Jørn
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - pharmacology Antipsychotics Attention - drug effects Attention - physiology Behavioral Sciences Biological Psychology Imidazoles - pharmacology Indoles - pharmacology Male Medicine Medicine & Public Health Neurosciences original-article Pharmacotherapy Phencyclidine - administration & dosage Phencyclidine - antagonists & inhibitors Psychiatry Rats Rats, Long-Evans Receptors, Serotonin - metabolism Receptors, Serotonin - physiology Serotonin Antagonists - pharmacology
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