Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo

Beta-catenin is thought to mediate cell fate specification events by localizing to the nucleus where it modulates gene expression. To ask whether beta-catenin is involved in cell fate specification during sea urchin embryogenesis, we analyzed the distribution of nuclear beta-catenin in both normal a...

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Veröffentlicht in:	Development (Cambridge) 1999-01, Vol.126 (2), p.345-357
Hauptverfasser:	Logan, C Y, Miller, J R, Ferkowicz, M J, McClay, D R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin Cadherins - genetics Carbocyanines - metabolism Cell Differentiation - physiology Cytoskeletal Proteins - metabolism Embryo, Nonmammalian - cytology Embryonic Development Endoderm - metabolism Gene Expression Regulation, Developmental - genetics Immunohistochemistry Lithium Chloride - pharmacology Mesoderm - metabolism Microinjections Microscopy, Confocal Nuclear Proteins - metabolism RNA, Messenger - genetics Sea Urchins - embryology Trans-Activators
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