Functional testosterone receptors in plasma membranes of T cells

ABSTRACT T cells are considered to be unresponsive to testosterone due to the absence of androgen receptors (AR). Here, we demonstrate the testosterone responsiveness of murine splenic T cells in vitro as well as the presence of unconventional cell surface receptors for testosterone and classical in...

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Veröffentlicht in:	The FASEB journal 1999-01, Vol.13 (1), p.123-133
Hauptverfasser:	BENTEN, W. Peter M., LIEBERHERR, MICHELE, GIESE, GüNTER, WREHLKE, CHRISTIAN, STAMM, OLAF, SEKERIS, CONSTANTIN E., MOSSMANN, HORST, WUNDERLICH, FRANK
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV androgen receptor Animals Binding Sites Ca2+ influx Calcium - metabolism CD4-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - metabolism Cell Membrane - metabolism Humans membrane receptor Mice Mice, Inbred C57BL Receptors, Androgen - genetics Receptors, Androgen - metabolism Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - metabolism Serum Albumin, Bovine - metabolism sex steroids Testosterone - metabolism Tumor Cells, Cultured
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