Osteoarthritis
Osteoarthritis (OA) is a chronic degenerative disorder characterized by cartilage loss. Its prevalence is high, and it is a major cause of disability. The cause of OA is not known; however, current evidence indicates that it is multifactorial. Major risk factors for osteoarthritis are age, female se...
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| Veröffentlicht in: | Best practice & research. Clinical rheumatology 2008-08, Vol.22 (4), p.657-675 |
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| container_title | Best practice & research. Clinical rheumatology |
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| creator | Das, Siddharth Kumar Farooqi, Abid |
| description | Osteoarthritis (OA) is a chronic degenerative disorder characterized by cartilage loss. Its prevalence is high, and it is a major cause of disability. The cause of OA is not known; however, current evidence indicates that it is multifactorial. Major risk factors for osteoarthritis are age, female sex, obesity, geographic factors, occupational knee-bending, physical labour, genetic factors and race, joint trauma, vitamin D deficiency, and chondrocalcinosis. Osteoarthritis causes joint pain, stiffness, and limitation of joint function. Knee involvement is the commonest presentation of this disease all over the world. Given the absence of a curative treatment, it is important to treat osteoarthritis as effectively as possible using a multidisciplinary approach tailored to the patient's needs. This article reviews current thinking on the epidemiology, clinical presentation, lifestyle, genetic epidemiology, and management of osteoarthritis in developing countries. |
| doi_str_mv | 10.1016/j.berh.2008.07.002 |
| format | Article |
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This article reviews current thinking on the epidemiology, clinical presentation, lifestyle, genetic epidemiology, and management of osteoarthritis in developing countries.</description><identifier>ISSN: 1521-6942</identifier><identifier>EISSN: 1532-1770</identifier><identifier>DOI: 10.1016/j.berh.2008.07.002</identifier><identifier>PMID: 18783743</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>developing countries ; Developing Countries - statistics & numerical data ; epidemiology ; genetic epidemiology ; Genetic Predisposition to Disease ; Humans ; Life Style ; lifestyle effect ; management ; Osteoarthritis - epidemiology ; Osteoarthritis - pathology ; Osteoarthritis - therapy ; Rheumatology ; Risk Factors ; vitamin D</subject><ispartof>Best practice & research. 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This article reviews current thinking on the epidemiology, clinical presentation, lifestyle, genetic epidemiology, and management of osteoarthritis in developing countries.</description><subject>developing countries</subject><subject>Developing Countries - statistics & numerical data</subject><subject>epidemiology</subject><subject>genetic epidemiology</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Life Style</subject><subject>lifestyle effect</subject><subject>management</subject><subject>Osteoarthritis - epidemiology</subject><subject>Osteoarthritis - pathology</subject><subject>Osteoarthritis - therapy</subject><subject>Rheumatology</subject><subject>Risk Factors</subject><subject>vitamin D</subject><issn>1521-6942</issn><issn>1532-1770</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU9LxDAQxYMo7rrqB_Dg0VvrJGmaBESQxX-wsAf1HNJ0yqZ2t2vSCvvtbdkFwYOnmcN7b5jfI-SKQkqB5rd1WmBYpQxApSBTAHZEplRwllAp4XjcGU1ynbEJOYuxBuBcs-yUTKiSisuMT8nlMnbY2tCtgu98PCcnlW0iXhzmjHw8Pb7PX5LF8vl1_rBIXMazLhF5pUQOpVKoKM2FRiewEAiVprlVpRhOIbVClk7ygtNMQaFRM15QW2gLfEZu9rnb0H71GDuz9tFh09gNtn00uRZcap4PQrYXutDGGLAy2-DXNuwMBTNSMLUZKZiRggFpBgqD6fqQ3hdrLH8th7cHwd1egMOP3x6Dic7jxmHpA7rOlK3_P__-j901fuOdbT5xh7Fu-7AZ6BlqIjNg3sYexhpAAYDkmv8ADFyANQ</recordid><startdate>20080801</startdate><enddate>20080801</enddate><creator>Das, Siddharth Kumar</creator><creator>Farooqi, Abid</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080801</creationdate><title>Osteoarthritis</title><author>Das, Siddharth Kumar ; Farooqi, Abid</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-56f8560d88e811659ec5eb5e0f916a8d5003e1a57dc73b31480b9e923b1ab9a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>developing countries</topic><topic>Developing Countries - statistics & numerical data</topic><topic>epidemiology</topic><topic>genetic epidemiology</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Life Style</topic><topic>lifestyle effect</topic><topic>management</topic><topic>Osteoarthritis - epidemiology</topic><topic>Osteoarthritis - pathology</topic><topic>Osteoarthritis - therapy</topic><topic>Rheumatology</topic><topic>Risk Factors</topic><topic>vitamin D</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Das, Siddharth Kumar</creatorcontrib><creatorcontrib>Farooqi, Abid</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Best practice & research. 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| fulltext | fulltext |
| identifier | ISSN: 1521-6942 |
| ispartof | Best practice & research. Clinical rheumatology, 2008-08, Vol.22 (4), p.657-675 |
| issn | 1521-6942 1532-1770 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | developing countries Developing Countries - statistics & numerical data epidemiology genetic epidemiology Genetic Predisposition to Disease Humans Life Style lifestyle effect management Osteoarthritis - epidemiology Osteoarthritis - pathology Osteoarthritis - therapy Rheumatology Risk Factors vitamin D |
| title | Osteoarthritis |
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