Degenerative dementia of the frontal type : Clinical evidence from 9 cases
The retrospective neurological, neuroradiological and neuropsychological observation of 9 cases of dementia with frontal symptoms is reported. Aim of this paper is to contribute to the clinical corpus of data related to the frontal features of the frontotemporal dementia (FTD) syndrome, so as to sup...
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| Veröffentlicht in: | Dementia and geriatric cognitive disorders 1999, Vol.10 (1), p.28-39 |
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| creator | GALANTE, E MUGGIA, S SPINNLER, H ZUFFI, M |
| description | The retrospective neurological, neuroradiological and neuropsychological observation of 9 cases of dementia with frontal symptoms is reported. Aim of this paper is to contribute to the clinical corpus of data related to the frontal features of the frontotemporal dementia (FTD) syndrome, so as to support clinicians' awareness and widen the information available for the diagnostic approach to the dementias. FTD is a clinical diagnosis which does not imply a single underlying pathology, since more than one condition can induce the syndrome. Inertia and behavioural symptoms were the traits characterizing both the onset and the progression of the disease in our patients. Progression brought to the surface behavioural and neuropsychological patterns generically traced back to frontal dysfunction. Social inadequacy was the most salient trait. From a clinical point of view frontal dementias may be regarded as a conceptually different type of dementia with respect to Alzheimer's disease, i.e., a 'behavioural' as opposed to a 'cognitive' progressive disorder. |
| doi_str_mv | 10.1159/000017094 |
| format | Article |
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Aim of this paper is to contribute to the clinical corpus of data related to the frontal features of the frontotemporal dementia (FTD) syndrome, so as to support clinicians' awareness and widen the information available for the diagnostic approach to the dementias. FTD is a clinical diagnosis which does not imply a single underlying pathology, since more than one condition can induce the syndrome. Inertia and behavioural symptoms were the traits characterizing both the onset and the progression of the disease in our patients. Progression brought to the surface behavioural and neuropsychological patterns generically traced back to frontal dysfunction. Social inadequacy was the most salient trait. 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Aim of this paper is to contribute to the clinical corpus of data related to the frontal features of the frontotemporal dementia (FTD) syndrome, so as to support clinicians' awareness and widen the information available for the diagnostic approach to the dementias. FTD is a clinical diagnosis which does not imply a single underlying pathology, since more than one condition can induce the syndrome. Inertia and behavioural symptoms were the traits characterizing both the onset and the progression of the disease in our patients. Progression brought to the surface behavioural and neuropsychological patterns generically traced back to frontal dysfunction. Social inadequacy was the most salient trait. From a clinical point of view frontal dementias may be regarded as a conceptually different type of dementia with respect to Alzheimer's disease, i.e., a 'behavioural' as opposed to a 'cognitive' progressive disorder.</description><subject>Adult</subject><subject>Age of Onset</subject><subject>Aged</subject><subject>Behavior</subject><subject>Biological and medical sciences</subject><subject>Cognition - physiology</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Dementia</subject><subject>Dementia - diagnostic imaging</subject><subject>Dementia - pathology</subject><subject>Dementia - psychology</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Frontal Lobe - diagnostic imaging</subject><subject>Frontal Lobe - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Radiography</subject><issn>1420-8008</issn><issn>1421-9824</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpd0EtLxDAQAOAgyqqrB3-AEES8VfNu4k3WNwte9FzSdKJZ-libdmH_vWEtHpzLTJiPYSYInVFyTak0NyQFzYkRe-iICkYzo5nY39Uk04ToQ3Qc4yqpXCozQzOjhSBcHqHXe_iEFno7hA3gChpoh2Bx5_HwBdj3XTvYGg_bNeBbvKhDG1x6wyZU0LodaLDBzkaIJ-jA2zrC6ZTn6OPx4X3xnC3fnl4Wd8tszRQbMglCGnA5JVITnYtKG1kKy7wqXVlpxpiilgqqqCupr3SpgVjwHCBXFeWez9HV79x1332PEIeiCdFBXdsWujEWykguOWUJXvyDq27s27RbwTgTJheEJHQ-obFsoCrWfWhsvy2mH0r9y6lvYzrd97Z1If4xqkiujOE_mqVxag</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>GALANTE, E</creator><creator>MUGGIA, S</creator><creator>SPINNLER, H</creator><creator>ZUFFI, M</creator><general>Karger</general><general>S. 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Aim of this paper is to contribute to the clinical corpus of data related to the frontal features of the frontotemporal dementia (FTD) syndrome, so as to support clinicians' awareness and widen the information available for the diagnostic approach to the dementias. FTD is a clinical diagnosis which does not imply a single underlying pathology, since more than one condition can induce the syndrome. Inertia and behavioural symptoms were the traits characterizing both the onset and the progression of the disease in our patients. Progression brought to the surface behavioural and neuropsychological patterns generically traced back to frontal dysfunction. Social inadequacy was the most salient trait. From a clinical point of view frontal dementias may be regarded as a conceptually different type of dementia with respect to Alzheimer's disease, i.e., a 'behavioural' as opposed to a 'cognitive' progressive disorder.</abstract><cop>Basel</cop><pub>Karger</pub><pmid>9844035</pmid><doi>10.1159/000017094</doi><tpages>12</tpages></addata></record> |
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| subjects | Adult Age of Onset Aged Behavior Biological and medical sciences Cognition - physiology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia Dementia - diagnostic imaging Dementia - pathology Dementia - psychology Diagnosis, Differential Female Frontal Lobe - diagnostic imaging Frontal Lobe - pathology Humans Male Medical sciences Middle Aged Neurology Neuropsychological Tests Radiography |
| title | Degenerative dementia of the frontal type : Clinical evidence from 9 cases |
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