The combination of high cyclin E and Skp2 expression in breast cancer is associated with a poor prognosis and the basal phenotype

Summary Gene expression studies have identified a basal phenotype of breast cancer; these are hormone receptor and HER2-negative cancers with poor prognosis. High levels of cyclin E and Skp2, and low levels of p27 have previously been individually associated with both basal-like breast cancer and a...

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Veröffentlicht in:Human pathology 2008-10, Vol.39 (10), p.1431-1437
Hauptverfasser: Voduc, David, MD, FRCPC, Nielsen, Torsten O., MD, PhD, Cheang, Maggie C., MMedSc, Foulkes, William D., MD, PhD
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Sprache:eng
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