Transcriptional control of skeletogenesis

The skeleton contains three specific cell types: chondrocytes in cartilage and osteoblasts and osteoclasts in bone. Our understanding of the transcriptional mechanisms that lead to cell differentiation along these three lineages has increased considerably in the past ten years. In the case of chondr...

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Veröffentlicht in:	Annual review of genomics and human genetics 2008-01, Vol.9 (1), p.183-196
1. Verfasser:	Karsenty, Gerard
Format:	Artikel
Sprache:	eng
Schlagworte:	Activating Transcription Factor 4 - genetics Animals Bone Development - genetics Bone Diseases, Developmental - genetics Cell Differentiation - genetics Chondrogenesis - genetics Core Binding Factor Alpha 1 Subunit - genetics Humans Mice Models, Genetic Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - genetics Sp7 Transcription Factor Transcription Factor AP-1 - genetics Transcription Factors - genetics Transcription, Genetic
Online-Zugang:	Volltext
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