Nonenzymatic Synthesis of RNA and DNA Oligomers on Hexitol Nucleic Acid Templates:  The Importance of the A Structure

Hexitol nucleic acid (HNA) is an analogue of DNA containing the standard nucleoside bases, but with a phosphorylated 1,5-anhydrohexitol backbone. HNA oligomers form duplexes having the nucleic acid A structure with complementary DNA or RNA oligomers. The HNA decacytidylate oligomer is an efficient t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 1999-03, Vol.121 (12), p.2653-2656
Hauptverfasser: Kozlov, Igor A, Politis, Panagiotis K, Van Aerschot, Arthur, Busson, Roger, Herdewijn, Piet, Orgel, Leslie E
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!