Modulation of cholinergic contractions of airway smooth muscle by cathinone: potential beneficial effects in airway diseases

Infusion of khat leaves is an African traditional remedy used to treat airway diseases. The beneficial effects of khat are thought to be due to the activity of its main active component, cathinone. Cathinone inhibited electric field stimulation-induced acetylcholine release and the contractions of s...

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Veröffentlicht in:	The European respiratory journal 2008-09, Vol.32 (3), p.579-584
Hauptverfasser:	Freund-Michel, V. C, Birrell, M. A, Patel, H. J, Murray-Lyon, I. M, Belvisi, M. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Biological and medical sciences Central Nervous System Stimulants - pharmacology Guinea Pigs Humans In Vitro Techniques Lung - drug effects Male Medical sciences Muscle Contraction - drug effects Muscle, Smooth - drug effects Parasympathetic Nervous System - drug effects Pneumology Trachea - drug effects Vas Deferens - drug effects
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