Diagnosis and Management of Lymphatic Vascular Disease
Diagnosis and Management of Lymphatic Vascular Disease Stanley G. Rockson In health, the lymphatic vasculature possesses the requisite transport capacity to accommodate the fluid load placed upon it. The most readily recognizable attribute of lymphatic vascular incompetence is the presence of lymphe...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2008-09, Vol.52 (10), p.799-806 |
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| creator | Rockson, Stanley G., MD |
| description | Diagnosis and Management of Lymphatic Vascular Disease Stanley G. Rockson In health, the lymphatic vasculature possesses the requisite transport capacity to accommodate the fluid load placed upon it. The most readily recognizable attribute of lymphatic vascular incompetence is the presence of lymphedema, which arises as a consequence of insufficient lymph transport. The diagnosis of lymphatic disease relies heavily upon the physical examination. The state-of-the-art therapeutic approach to lymphedema relies upon physiotherapeutic techniques. The application of pharmacological therapies has been notably absent from the management strategies for lymphatic vascular insufficiency states. In the future, specifically engineered molecular therapeutics may facilitate the controlled regrowth of damaged, dysfunctional, or obliterated lymphatic vasculature. |
| doi_str_mv | 10.1016/j.jacc.2008.06.005 |
| format | Article |
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Rockson In health, the lymphatic vasculature possesses the requisite transport capacity to accommodate the fluid load placed upon it. The most readily recognizable attribute of lymphatic vascular incompetence is the presence of lymphedema, which arises as a consequence of insufficient lymph transport. The diagnosis of lymphatic disease relies heavily upon the physical examination. The state-of-the-art therapeutic approach to lymphedema relies upon physiotherapeutic techniques. The application of pharmacological therapies has been notably absent from the management strategies for lymphatic vascular insufficiency states. 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Rockson In health, the lymphatic vasculature possesses the requisite transport capacity to accommodate the fluid load placed upon it. The most readily recognizable attribute of lymphatic vascular incompetence is the presence of lymphedema, which arises as a consequence of insufficient lymph transport. The diagnosis of lymphatic disease relies heavily upon the physical examination. The state-of-the-art therapeutic approach to lymphedema relies upon physiotherapeutic techniques. The application of pharmacological therapies has been notably absent from the management strategies for lymphatic vascular insufficiency states. In the future, specifically engineered molecular therapeutics may facilitate the controlled regrowth of damaged, dysfunctional, or obliterated lymphatic vasculature.</description><subject>Biological and medical sciences</subject><subject>Breast cancer</subject><subject>Cancer therapies</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Cardiovascular Diseases - diagnosis</subject><subject>Cardiovascular Diseases - drug therapy</subject><subject>Cardiovascular Diseases - metabolism</subject><subject>Cardiovascular Diseases - therapy</subject><subject>edema</subject><subject>Fluids</subject><subject>Gene therapy</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Internal Medicine</subject><subject>Ligands</subject><subject>Lymphangiogenesis</subject><subject>lymphatic</subject><subject>Lymphatic Diseases - diagnosis</subject><subject>Lymphatic Diseases - drug therapy</subject><subject>Lymphatic Diseases - metabolism</subject><subject>Lymphatic Diseases - therapy</subject><subject>Lymphatic system</subject><subject>lymphatic vascular disease</subject><subject>lymphedema</subject><subject>Lymphedema - diagnosis</subject><subject>Lymphedema - therapy</subject><subject>Medical sciences</subject><subject>Pain</subject><subject>Physical Therapy Modalities</subject><subject>Proteins</subject><subject>Receptors, Vascular Endothelial Growth Factor - metabolism</subject><subject>Rodents</subject><subject>Vascular endothelial growth factor</subject><subject>Vascular Endothelial Growth Factor A - metabolism</subject><subject>vascular insufficiency</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFksuL1EAQhxtR3NnVf8CDBMS9JVZ30o-ACLLrC0Y8-Lg2lU5l7ZhJZrsTYf57O8zgwh70VJfvV4-PYuwZh4IDV6_6okfnCgFgClAFgHzANlxKk5ey1g_ZBnQpcw61PmPnMfYAoAyvH7MzbrSUZcU3TF17vBmn6GOGY5t9xhFvaEfjnE1dtj3s9j9x9i77gdEtA4bs2kfCSE_Yow6HSE9P9YJ9f__u29XHfPvlw6ert9vcSa3nXNVdw0sUSnal4NygdiQEyaZqoEPNW1WjxppQVa422JBWvOGNdMK4qq5UecEuj333YbpdKM5256OjYcCRpiVaVVemqvn_QQFClSBNAl_cA_tpCWM6wnJVyeTVKJEocaRcmGIM1Nl98DsMB8vBrvJtb1f5dpVvQdkkP4Wen1ovzY7au8jJdgJenoCkE4cu4Oh8_MsJSJOV0ol7feQoqf3tKdjoPI2OWh_Izbad_L_3eHMv7gY_-jTxFx0o3t1ro7Bgv65vsn4JGBAcgJd_AHt-tJo</recordid><startdate>20080902</startdate><enddate>20080902</enddate><creator>Rockson, Stanley G., MD</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20080902</creationdate><title>Diagnosis and Management of Lymphatic Vascular Disease</title><author>Rockson, Stanley G., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c577t-69fb13a265f32118a7ce22e5b4b0fa71d69a7a9ea64c98abe761b1b5c28c49463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Biological and medical sciences</topic><topic>Breast cancer</topic><topic>Cancer therapies</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Cardiovascular Diseases - diagnosis</topic><topic>Cardiovascular Diseases - drug therapy</topic><topic>Cardiovascular Diseases - metabolism</topic><topic>Cardiovascular Diseases - therapy</topic><topic>edema</topic><topic>Fluids</topic><topic>Gene therapy</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Internal Medicine</topic><topic>Ligands</topic><topic>Lymphangiogenesis</topic><topic>lymphatic</topic><topic>Lymphatic Diseases - diagnosis</topic><topic>Lymphatic Diseases - drug therapy</topic><topic>Lymphatic Diseases - metabolism</topic><topic>Lymphatic Diseases - therapy</topic><topic>Lymphatic system</topic><topic>lymphatic vascular disease</topic><topic>lymphedema</topic><topic>Lymphedema - diagnosis</topic><topic>Lymphedema - therapy</topic><topic>Medical sciences</topic><topic>Pain</topic><topic>Physical Therapy Modalities</topic><topic>Proteins</topic><topic>Receptors, Vascular Endothelial Growth Factor - metabolism</topic><topic>Rodents</topic><topic>Vascular endothelial growth factor</topic><topic>Vascular Endothelial Growth Factor A - metabolism</topic><topic>vascular insufficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rockson, Stanley G., MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rockson, Stanley G., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosis and Management of Lymphatic Vascular Disease</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2008-09-02</date><risdate>2008</risdate><volume>52</volume><issue>10</issue><spage>799</spage><epage>806</epage><pages>799-806</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>Diagnosis and Management of Lymphatic Vascular Disease Stanley G. Rockson In health, the lymphatic vasculature possesses the requisite transport capacity to accommodate the fluid load placed upon it. The most readily recognizable attribute of lymphatic vascular incompetence is the presence of lymphedema, which arises as a consequence of insufficient lymph transport. The diagnosis of lymphatic disease relies heavily upon the physical examination. The state-of-the-art therapeutic approach to lymphedema relies upon physiotherapeutic techniques. The application of pharmacological therapies has been notably absent from the management strategies for lymphatic vascular insufficiency states. In the future, specifically engineered molecular therapeutics may facilitate the controlled regrowth of damaged, dysfunctional, or obliterated lymphatic vasculature.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18755341</pmid><doi>10.1016/j.jacc.2008.06.005</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Breast cancer Cancer therapies Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular Diseases - diagnosis Cardiovascular Diseases - drug therapy Cardiovascular Diseases - metabolism Cardiovascular Diseases - therapy edema Fluids Gene therapy Homeostasis Humans Hypertension Internal Medicine Ligands Lymphangiogenesis lymphatic Lymphatic Diseases - diagnosis Lymphatic Diseases - drug therapy Lymphatic Diseases - metabolism Lymphatic Diseases - therapy Lymphatic system lymphatic vascular disease lymphedema Lymphedema - diagnosis Lymphedema - therapy Medical sciences Pain Physical Therapy Modalities Proteins Receptors, Vascular Endothelial Growth Factor - metabolism Rodents Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism vascular insufficiency |
| title | Diagnosis and Management of Lymphatic Vascular Disease |
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