Serotonin and dopamine transporter binding in children with autism determined by SPECT

Disturbances in the serotonergic system have been recognized in autism. To investigate the association between serotonin and dopamine transporters and autism, we studied 15 children (14 males, one female; mean age 8y 8mo [SD 3y 10mo]) with autism and 10 non‐autistic comparison children (five males,...

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Veröffentlicht in:	Developmental medicine and child neurology 2008-08, Vol.50 (8), p.593-597
Hauptverfasser:	Makkonen, Ismo, Riikonen, Raili, Kokki, Hannu, Airaksinen, Mauno M, Kuikka, Jyrki T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Algorithms Anatomy Autism Autistic Disorder - diagnostic imaging Autistic Disorder - metabolism Binding Sites Biochemistry Brain Brain - diagnostic imaging Brain - metabolism Brain Hemisphere Functions Cerebellum - diagnostic imaging Cerebellum - metabolism Child Children Comparative Analysis Computation Corpus Striatum - diagnostic imaging Corpus Striatum - metabolism Correlation Diagnostic Tests Dopamine Plasma Membrane Transport Proteins - metabolism Drug Use Ethics Female Fetal Alcohol Syndrome Genetics Humans Interpersonal Relationship Male Males Medical Services Mesencephalon - diagnostic imaging Mesencephalon - metabolism Motor Vehicles Neurology Nonverbal Communication Patients Radiation Rating Scales Regression (Statistics) Serotonin Plasma Membrane Transport Proteins - metabolism Statistical Analysis Temporal Lobe - diagnostic imaging Temporal Lobe - metabolism Tomography, Emission-Computed, Single-Photon
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