Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents
Purpose: To investigate the effect of multislice computed tomography (CT) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts. Methods: Twenty-one patients (19 men; mean age 75 years, range 63–86) underg...
Gespeichert in:
Veröffentlicht in: | Journal of endovascular therapy 2008-08, Vol.15 (4), p.417-426 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 426 |
---|---|
container_issue | 4 |
container_start_page | 417 |
container_title | Journal of endovascular therapy |
container_volume | 15 |
creator | Sun, Zhonghua Allen, Yvonne B. Mwipatayi, Bibombe P. Hartley, David E. Lawrence-Brown, Michael M.D. |
description | Purpose:
To investigate the effect of multislice computed tomography (CT) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts.
Methods:
Twenty-one patients (19 men; mean age 75 years, range 63–86) undergoing fenestrated endovascular repair of AAA were retrospectively studied. Multislice CT angiography was performed with several protocols, and the section thicknesses used in each were compared to identify any relationship between slice thickness and target vessel stents visualized on 2-dimensional (2D) axial, multiplanar reformatted (MPR), and 3-dimensional (3D) virtual intravascular endoscopy (VIE) images. Image quality was assessed based on the degree of artifacts and their effect on the ability to visualize the configuration, intra-aortic location, and intraluminal appearance of the target vessel stents and measure their protrusion into the aortic lumen.
Results:
There were 7 different multislice CT scanning protocols employed in the 21 patients (25 datasets, with 2 sets of follow-up images in 4 patients). The slice thicknesses and numbers (n) of studies included were 0.5 (n=3), 0.625 (n=6), 1.0 (n=1), 1.25 (n=9), 2.5 (n=3), 3.0 (n=1), and 5.0 mm (n=2). Of these CT protocols, images (especially 2D/3D reconstructions) acquired at 2.5, 3.0, and 5.0 mm were significantly compromised by interference from artifacts. Images acquired with a slice thickness of 1.0 or 1.25 mm were scored equal to or lower than those acquired with a submillimeter section thickness (0.5 or 0.625 mm), with minor degrees of artifacts resulting in acceptable image quality.
Conclusion:
Visualization of the target vessel stents depends on the appropriate selection of multislice CT scanning protocols. Our results showed that studies performed with a slice thickness of 1.0 or 1.25 mm produced similar image quality to those with a thickness of 0.5 or 0.625 mm. Submillimeter slices are not recommended in imaging patients treated with fenestrated stent-grafts, as they did not add additional information to the visualization. |
doi_str_mv | 10.1583/08-2432.1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69477704</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1583_08-2432.1</sage_id><sourcerecordid>69477704</sourcerecordid><originalsourceid>FETCH-LOGICAL-c341t-4667ae3ed3d5404ff048113e00a56880b21e547555b7aac5117be45794e3cf8a3</originalsourceid><addsrcrecordid>eNplkc1uEzEURi0EoqWw4AWQxQKJxRRf_4wn7Ko0KUhFLBrYWs7MncRlYgfbAyoPw7PiaYMiwcrW1fG5n_wR8hLYOahGvGNNxaXg5_CInIKSqgKl2OPpzuuqZrw5Ic9SumWMAwd4Sk6g0Xymajglvz-NQ3ZpcC3S-Ype-I0Lm2j32zvqPM1bpMswDOFnNe5p6OkSPaYcbcaOLnwXftjUjoON9CraPqf3dNH32OYJvbl3rrau_VbeJBo85ZfU-o6KS_rVpdEO7pfNrswLfb_pr3ya3WT0OT0nT3o7JHxxOM_Il-ViNf9QXX---ji_uK5aISFXsq61RYGd6JRksu-ZbAAEMmZV3TRszQGV1Eqptba2VQB6jVLpmUTR9o0VZ-TNg3cfw_expDA7l1ocBusxjMnUM6m1ZrKAr_8Bb8MYfclmyteCUErzAr19gNoYUorYm310OxvvDDAzNWZYY6bGDBT21UE4rnfYHclDRcdoyW7wuO1_0x-iDpv9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>211135572</pqid></control><display><type>article</type><title>Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents</title><source>Access via SAGE</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Sun, Zhonghua ; Allen, Yvonne B. ; Mwipatayi, Bibombe P. ; Hartley, David E. ; Lawrence-Brown, Michael M.D.</creator><creatorcontrib>Sun, Zhonghua ; Allen, Yvonne B. ; Mwipatayi, Bibombe P. ; Hartley, David E. ; Lawrence-Brown, Michael M.D.</creatorcontrib><description>Purpose:
To investigate the effect of multislice computed tomography (CT) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts.
Methods:
Twenty-one patients (19 men; mean age 75 years, range 63–86) undergoing fenestrated endovascular repair of AAA were retrospectively studied. Multislice CT angiography was performed with several protocols, and the section thicknesses used in each were compared to identify any relationship between slice thickness and target vessel stents visualized on 2-dimensional (2D) axial, multiplanar reformatted (MPR), and 3-dimensional (3D) virtual intravascular endoscopy (VIE) images. Image quality was assessed based on the degree of artifacts and their effect on the ability to visualize the configuration, intra-aortic location, and intraluminal appearance of the target vessel stents and measure their protrusion into the aortic lumen.
Results:
There were 7 different multislice CT scanning protocols employed in the 21 patients (25 datasets, with 2 sets of follow-up images in 4 patients). The slice thicknesses and numbers (n) of studies included were 0.5 (n=3), 0.625 (n=6), 1.0 (n=1), 1.25 (n=9), 2.5 (n=3), 3.0 (n=1), and 5.0 mm (n=2). Of these CT protocols, images (especially 2D/3D reconstructions) acquired at 2.5, 3.0, and 5.0 mm were significantly compromised by interference from artifacts. Images acquired with a slice thickness of 1.0 or 1.25 mm were scored equal to or lower than those acquired with a submillimeter section thickness (0.5 or 0.625 mm), with minor degrees of artifacts resulting in acceptable image quality.
Conclusion:
Visualization of the target vessel stents depends on the appropriate selection of multislice CT scanning protocols. Our results showed that studies performed with a slice thickness of 1.0 or 1.25 mm produced similar image quality to those with a thickness of 0.5 or 0.625 mm. Submillimeter slices are not recommended in imaging patients treated with fenestrated stent-grafts, as they did not add additional information to the visualization.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1583/08-2432.1</identifier><identifier>PMID: 18729561</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Aged ; Aged, 80 and over ; Angiography - methods ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Aortic Aneurysm, Abdominal - therapy ; Clinical outcomes ; Digital imaging ; Female ; Follow-Up Studies ; Humans ; Imaging, Three-Dimensional ; Linear Models ; Male ; Medical imaging ; Middle Aged ; Patients ; Protocol ; Radiographic Image Interpretation, Computer-Assisted ; Retrospective Studies ; Stents ; Tomography, X-Ray Computed - methods ; Veins & arteries</subject><ispartof>Journal of endovascular therapy, 2008-08, Vol.15 (4), p.417-426</ispartof><rights>2008 SAGE Publications</rights><rights>Copyright Allen Press Publishing Services Aug 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-4667ae3ed3d5404ff048113e00a56880b21e547555b7aac5117be45794e3cf8a3</citedby><cites>FETCH-LOGICAL-c341t-4667ae3ed3d5404ff048113e00a56880b21e547555b7aac5117be45794e3cf8a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1583/08-2432.1$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1583/08-2432.1$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18729561$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sun, Zhonghua</creatorcontrib><creatorcontrib>Allen, Yvonne B.</creatorcontrib><creatorcontrib>Mwipatayi, Bibombe P.</creatorcontrib><creatorcontrib>Hartley, David E.</creatorcontrib><creatorcontrib>Lawrence-Brown, Michael M.D.</creatorcontrib><title>Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>Purpose:
To investigate the effect of multislice computed tomography (CT) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts.
Methods:
Twenty-one patients (19 men; mean age 75 years, range 63–86) undergoing fenestrated endovascular repair of AAA were retrospectively studied. Multislice CT angiography was performed with several protocols, and the section thicknesses used in each were compared to identify any relationship between slice thickness and target vessel stents visualized on 2-dimensional (2D) axial, multiplanar reformatted (MPR), and 3-dimensional (3D) virtual intravascular endoscopy (VIE) images. Image quality was assessed based on the degree of artifacts and their effect on the ability to visualize the configuration, intra-aortic location, and intraluminal appearance of the target vessel stents and measure their protrusion into the aortic lumen.
Results:
There were 7 different multislice CT scanning protocols employed in the 21 patients (25 datasets, with 2 sets of follow-up images in 4 patients). The slice thicknesses and numbers (n) of studies included were 0.5 (n=3), 0.625 (n=6), 1.0 (n=1), 1.25 (n=9), 2.5 (n=3), 3.0 (n=1), and 5.0 mm (n=2). Of these CT protocols, images (especially 2D/3D reconstructions) acquired at 2.5, 3.0, and 5.0 mm were significantly compromised by interference from artifacts. Images acquired with a slice thickness of 1.0 or 1.25 mm were scored equal to or lower than those acquired with a submillimeter section thickness (0.5 or 0.625 mm), with minor degrees of artifacts resulting in acceptable image quality.
Conclusion:
Visualization of the target vessel stents depends on the appropriate selection of multislice CT scanning protocols. Our results showed that studies performed with a slice thickness of 1.0 or 1.25 mm produced similar image quality to those with a thickness of 0.5 or 0.625 mm. Submillimeter slices are not recommended in imaging patients treated with fenestrated stent-grafts, as they did not add additional information to the visualization.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiography - methods</subject><subject>Aortic Aneurysm, Abdominal - diagnostic imaging</subject><subject>Aortic Aneurysm, Abdominal - therapy</subject><subject>Clinical outcomes</subject><subject>Digital imaging</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Linear Models</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Protocol</subject><subject>Radiographic Image Interpretation, Computer-Assisted</subject><subject>Retrospective Studies</subject><subject>Stents</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Veins & arteries</subject><issn>1526-6028</issn><issn>1545-1550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNplkc1uEzEURi0EoqWw4AWQxQKJxRRf_4wn7Ko0KUhFLBrYWs7MncRlYgfbAyoPw7PiaYMiwcrW1fG5n_wR8hLYOahGvGNNxaXg5_CInIKSqgKl2OPpzuuqZrw5Ic9SumWMAwd4Sk6g0Xymajglvz-NQ3ZpcC3S-Ype-I0Lm2j32zvqPM1bpMswDOFnNe5p6OkSPaYcbcaOLnwXftjUjoON9CraPqf3dNH32OYJvbl3rrau_VbeJBo85ZfU-o6KS_rVpdEO7pfNrswLfb_pr3ya3WT0OT0nT3o7JHxxOM_Il-ViNf9QXX---ji_uK5aISFXsq61RYGd6JRksu-ZbAAEMmZV3TRszQGV1Eqptba2VQB6jVLpmUTR9o0VZ-TNg3cfw_expDA7l1ocBusxjMnUM6m1ZrKAr_8Bb8MYfclmyteCUErzAr19gNoYUorYm310OxvvDDAzNWZYY6bGDBT21UE4rnfYHclDRcdoyW7wuO1_0x-iDpv9</recordid><startdate>200808</startdate><enddate>200808</enddate><creator>Sun, Zhonghua</creator><creator>Allen, Yvonne B.</creator><creator>Mwipatayi, Bibombe P.</creator><creator>Hartley, David E.</creator><creator>Lawrence-Brown, Michael M.D.</creator><general>SAGE Publications</general><general>Allen Press Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200808</creationdate><title>Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents</title><author>Sun, Zhonghua ; Allen, Yvonne B. ; Mwipatayi, Bibombe P. ; Hartley, David E. ; Lawrence-Brown, Michael M.D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-4667ae3ed3d5404ff048113e00a56880b21e547555b7aac5117be45794e3cf8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiography - methods</topic><topic>Aortic Aneurysm, Abdominal - diagnostic imaging</topic><topic>Aortic Aneurysm, Abdominal - therapy</topic><topic>Clinical outcomes</topic><topic>Digital imaging</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Imaging, Three-Dimensional</topic><topic>Linear Models</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Protocol</topic><topic>Radiographic Image Interpretation, Computer-Assisted</topic><topic>Retrospective Studies</topic><topic>Stents</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sun, Zhonghua</creatorcontrib><creatorcontrib>Allen, Yvonne B.</creatorcontrib><creatorcontrib>Mwipatayi, Bibombe P.</creatorcontrib><creatorcontrib>Hartley, David E.</creatorcontrib><creatorcontrib>Lawrence-Brown, Michael M.D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of endovascular therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sun, Zhonghua</au><au>Allen, Yvonne B.</au><au>Mwipatayi, Bibombe P.</au><au>Hartley, David E.</au><au>Lawrence-Brown, Michael M.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents</atitle><jtitle>Journal of endovascular therapy</jtitle><addtitle>J Endovasc Ther</addtitle><date>2008-08</date><risdate>2008</risdate><volume>15</volume><issue>4</issue><spage>417</spage><epage>426</epage><pages>417-426</pages><issn>1526-6028</issn><eissn>1545-1550</eissn><abstract>Purpose:
To investigate the effect of multislice computed tomography (CT) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts.
Methods:
Twenty-one patients (19 men; mean age 75 years, range 63–86) undergoing fenestrated endovascular repair of AAA were retrospectively studied. Multislice CT angiography was performed with several protocols, and the section thicknesses used in each were compared to identify any relationship between slice thickness and target vessel stents visualized on 2-dimensional (2D) axial, multiplanar reformatted (MPR), and 3-dimensional (3D) virtual intravascular endoscopy (VIE) images. Image quality was assessed based on the degree of artifacts and their effect on the ability to visualize the configuration, intra-aortic location, and intraluminal appearance of the target vessel stents and measure their protrusion into the aortic lumen.
Results:
There were 7 different multislice CT scanning protocols employed in the 21 patients (25 datasets, with 2 sets of follow-up images in 4 patients). The slice thicknesses and numbers (n) of studies included were 0.5 (n=3), 0.625 (n=6), 1.0 (n=1), 1.25 (n=9), 2.5 (n=3), 3.0 (n=1), and 5.0 mm (n=2). Of these CT protocols, images (especially 2D/3D reconstructions) acquired at 2.5, 3.0, and 5.0 mm were significantly compromised by interference from artifacts. Images acquired with a slice thickness of 1.0 or 1.25 mm were scored equal to or lower than those acquired with a submillimeter section thickness (0.5 or 0.625 mm), with minor degrees of artifacts resulting in acceptable image quality.
Conclusion:
Visualization of the target vessel stents depends on the appropriate selection of multislice CT scanning protocols. Our results showed that studies performed with a slice thickness of 1.0 or 1.25 mm produced similar image quality to those with a thickness of 0.5 or 0.625 mm. Submillimeter slices are not recommended in imaging patients treated with fenestrated stent-grafts, as they did not add additional information to the visualization.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>18729561</pmid><doi>10.1583/08-2432.1</doi><tpages>10</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1526-6028 |
ispartof | Journal of endovascular therapy, 2008-08, Vol.15 (4), p.417-426 |
issn | 1526-6028 1545-1550 |
language | eng |
recordid | cdi_proquest_miscellaneous_69477704 |
source | Access via SAGE; MEDLINE; Alma/SFX Local Collection |
subjects | Aged Aged, 80 and over Angiography - methods Aortic Aneurysm, Abdominal - diagnostic imaging Aortic Aneurysm, Abdominal - therapy Clinical outcomes Digital imaging Female Follow-Up Studies Humans Imaging, Three-Dimensional Linear Models Male Medical imaging Middle Aged Patients Protocol Radiographic Image Interpretation, Computer-Assisted Retrospective Studies Stents Tomography, X-Ray Computed - methods Veins & arteries |
title | Multislice CT Angiography in the Follow-up of Fenestrated Endovascular Grafts: Effect of Slice Thickness on 2D and 3D Visualization of the Fenestration Stents |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T01%3A14%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multislice%20CT%20Angiography%20in%20the%20Follow-up%20of%20Fenestrated%20Endovascular%20Grafts:%20Effect%20of%20Slice%20Thickness%20on%202D%20and%203D%20Visualization%20of%20the%20Fenestration%20Stents&rft.jtitle=Journal%20of%20endovascular%20therapy&rft.au=Sun,%20Zhonghua&rft.date=2008-08&rft.volume=15&rft.issue=4&rft.spage=417&rft.epage=426&rft.pages=417-426&rft.issn=1526-6028&rft.eissn=1545-1550&rft_id=info:doi/10.1583/08-2432.1&rft_dat=%3Cproquest_cross%3E69477704%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=211135572&rft_id=info:pmid/18729561&rft_sage_id=10.1583_08-2432.1&rfr_iscdi=true |