Total Synthesis of (±)-Methyl Rishirilide B

A regio- and stereospecific total synthesis of (±)-methyl rishirilide B (2b), an (α)2-macroglobulin inhibitor, is described. A key feature of the synthetic plan was regiospecific construction of a hydroanthracenone intermediate through condensation of a phenylsulfonyl isobenzofuranone with a functio...

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Veröffentlicht in:	Organic letters 1999-07, Vol.1 (2), p.335-336
Hauptverfasser:	Hauser, Frank M, Xu, Yong-jin
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Macroglobulins - antagonists & inhibitors Anthracenes - chemical synthesis Anthracenes - chemistry Fibrinolytic Agents - chemical synthesis Hydrolysis Indicators and Reagents Stereoisomerism Streptomyces - chemistry
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