Evidence for glycogenin autoglucosylation cessation by inaccessibility of the acquired maltosaccharide

Glycogenin initiates the biosynthesis of proteoglycogen, the mammalian glycogenin-bound glycogen, by intramolecular autoglucosylation. The incubation of glycogenin with UDP-glucose results in formation of a tyrosine-bound maltosaccharide, reaching maximum polymerization degree of 13 glucose units at...

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Veröffentlicht in:	Biochemical and biophysical research communications 2008-10, Vol.374 (4), p.704-708
Hauptverfasser:	Romero, Jorge M., Issoglio, Federico M., Carrizo, María E., Curtino, Juan A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoglucosylation Autoglucosylation cessation Catalysis Glucose - metabolism Glucosyltransferases - metabolism Glycogen - biosynthesis Glycogenin Glycoproteins - metabolism Glycosylation Maltose - metabolism Polysaccharide-bound glycogenin Proteoglycogen Rabbits Recombinant Proteins - metabolism Substrate Specificity
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