Direct Assessments of the Antioxidant Effects of Propofol Medium Chain Triglyceride/Long Chain Triglyceride on the Brain of Stroke-prone Spontaneously Hypertensive Rats Using Electron Spin Resonance Spectroscopy

Antioxidant anesthetics such as propofol (2,6-diisopropylphenol) directly inhibit lipid peroxidation via the generation of reactive oxygen species. Currently, there are no other studies regarding the direct effects of propofol medium chain triglyceride/long chain triglyceride (MCT/LCT) on reactive o...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2008-09, Vol.109 (3), p.426-435
Hauptverfasser:	KOBAYASHI, Kyo, YOSHINO, Fumihiko, TAKAHASHI, Shun-Suke, TODOKI, Kazuo, MAEHATA, Yojiro, KOMATSU, Tomoko, YOSHIDA, Kazu-Lchi, LEE, Masaichi-Chang-Il
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Intravenous - chemistry Anesthetics, Intravenous - pharmacology Animals Antioxidants - chemistry Antioxidants - pharmacology Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Brain - drug effects Brain - metabolism Cardiology. Vascular system Cerebrovascular Circulation - drug effects Disease Models, Animal Electron Spin Resonance Spectroscopy - methods Hydrogen Peroxide - chemistry Hydrogen Peroxide - radiation effects Iron - chemistry Lipid Peroxidation - drug effects Male Medical sciences Oxidative Stress - drug effects Propofol - chemistry Propofol - pharmacology Rats Rats, Inbred SHR Rats, Wistar Reactive Oxygen Species - metabolism Superoxides - metabolism Triglycerides - chemistry Triglycerides - pharmacology Ultraviolet Rays
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