Na+ Modulates Anion Permeation and Block of P2X7 Receptors from Mouse Parotid Glands

We previously reported that mouse parotid acinar cells display anion conductance ( I ATPCl ) when stimulated by external ATP in Na + -free extracellular solutions. It has been suggested that the P2X 7 receptor channel (P2X 7 R) might underlie I ATPCl . In this work we show that I ATPCl can be activa...

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Veröffentlicht in:	The Journal of membrane biology 2008-05, Vol.223 (2), p.73-85
Hauptverfasser:	Reyes, Juan Pablo, Pérez-Cornejo, Patricia, Hernández-Carballo, Carmen Y., Srivastava, Alaka, Romanenko, Victor G., Gonzalez-Begne, Mireya, Melvin, James E., Arreola, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Nucleotides - pharmacology Adenosine triphosphatase Adenosine Triphosphate - physiology Animals Anions - metabolism Biochemistry Biomedical and Life Sciences Cell Line Cellular biology Human Physiology Humans Life Sciences Membranes Mice Parotid Gland - cytology Parotid Gland - drug effects Parotid Gland - physiology Permeability - drug effects Receptors, Purinergic P2 - drug effects Receptors, Purinergic P2 - physiology Receptors, Purinergic P2X7 Rodents Sodium Sodium - physiology Triazines - pharmacology
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