Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures
We report for the first time the use of two photon fluorescence as detection method of affinity binding reactions. We use a resonant grating waveguide structure as platform enhancement for detecting the interaction between fluorescent labeled Boldenone, a non-natural androgenic hormone, and a specif...
Gespeichert in:
| Veröffentlicht in: | Optics express 2008-08, Vol.16 (17), p.13315-13322 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 13322 |
|---|---|
| container_issue | 17 |
| container_start_page | 13315 |
| container_title | Optics express |
| container_volume | 16 |
| creator | Thayil, Anisha Muriano, Alejandro Salvador, J-Pablo Galve, Roger Marco, Maria P Zalvidea, Dobryna Loza-Alvarez, Pablo Katchalski, Tsvi Grinvald, Eran Friesem, Asher A Soria, Silvia |
| description | We report for the first time the use of two photon fluorescence as detection method of affinity binding reactions. We use a resonant grating waveguide structure as platform enhancement for detecting the interaction between fluorescent labeled Boldenone, a non-natural androgenic hormone, and a specific anti-anabolic antibody. We were able to detect a surface coverage of approximately 0.7 ng/mm(2). |
| doi_str_mv | 10.1364/OE.16.013315 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69442094</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69442094</sourcerecordid><originalsourceid>FETCH-LOGICAL-c327t-c059a66bc051c7e11aadb60dc9cbfca4834b31448653f84e238ffb1121bc24513</originalsourceid><addsrcrecordid>eNpNkD1PwzAURS0EoqWwMSNPTKT4xY6TjAiVD6miC7BatmNDUGIXOx767zFqJZjufdLR1dNB6BLIEihnt5vVEviSAKVQHaE5kJYVjDT18b8-Q2cxfhECrG7rUzSDpgaoeDNH7y_eDb0zMuB-HJPzdkg-mKiNm7CMUe6w9QFL1wX_YVyv8acPo3cmYiWj6bB3OOPeyczHKSQ9pXyfoxMrh2guDrlAbw-r1_unYr15fL6_WxealvVUaFK1knOVE3RtAKTsFCedbrWyWrKGMkWBsYZX1DbMlLSxVgGUoHTJKqALdL3f3Qb_nUycxNjn34dBOuNTFLxlrMwWMnizB3XwMQZjxTb0oww7AUT8ehSblQAu9h4zfnXYTWo03R98EEd_AGAlb0E</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69442094</pqid></control><display><type>article</type><title>Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Thayil, Anisha ; Muriano, Alejandro ; Salvador, J-Pablo ; Galve, Roger ; Marco, Maria P ; Zalvidea, Dobryna ; Loza-Alvarez, Pablo ; Katchalski, Tsvi ; Grinvald, Eran ; Friesem, Asher A ; Soria, Silvia</creator><creatorcontrib>Thayil, Anisha ; Muriano, Alejandro ; Salvador, J-Pablo ; Galve, Roger ; Marco, Maria P ; Zalvidea, Dobryna ; Loza-Alvarez, Pablo ; Katchalski, Tsvi ; Grinvald, Eran ; Friesem, Asher A ; Soria, Silvia</creatorcontrib><description>We report for the first time the use of two photon fluorescence as detection method of affinity binding reactions. We use a resonant grating waveguide structure as platform enhancement for detecting the interaction between fluorescent labeled Boldenone, a non-natural androgenic hormone, and a specific anti-anabolic antibody. We were able to detect a surface coverage of approximately 0.7 ng/mm(2).</description><identifier>ISSN: 1094-4087</identifier><identifier>EISSN: 1094-4087</identifier><identifier>DOI: 10.1364/OE.16.013315</identifier><identifier>PMID: 18711568</identifier><language>eng</language><publisher>United States</publisher><subject>Androgens - analysis ; Biological Assay - instrumentation ; Biosensing Techniques - instrumentation ; Equipment Design ; Equipment Failure Analysis ; Immunoassay - instrumentation ; Microscopy, Fluorescence, Multiphoton - instrumentation ; Nonlinear Dynamics ; Photometry - instrumentation ; Refractometry - instrumentation ; Transducers</subject><ispartof>Optics express, 2008-08, Vol.16 (17), p.13315-13322</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c327t-c059a66bc051c7e11aadb60dc9cbfca4834b31448653f84e238ffb1121bc24513</citedby><cites>FETCH-LOGICAL-c327t-c059a66bc051c7e11aadb60dc9cbfca4834b31448653f84e238ffb1121bc24513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18711568$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thayil, Anisha</creatorcontrib><creatorcontrib>Muriano, Alejandro</creatorcontrib><creatorcontrib>Salvador, J-Pablo</creatorcontrib><creatorcontrib>Galve, Roger</creatorcontrib><creatorcontrib>Marco, Maria P</creatorcontrib><creatorcontrib>Zalvidea, Dobryna</creatorcontrib><creatorcontrib>Loza-Alvarez, Pablo</creatorcontrib><creatorcontrib>Katchalski, Tsvi</creatorcontrib><creatorcontrib>Grinvald, Eran</creatorcontrib><creatorcontrib>Friesem, Asher A</creatorcontrib><creatorcontrib>Soria, Silvia</creatorcontrib><title>Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures</title><title>Optics express</title><addtitle>Opt Express</addtitle><description>We report for the first time the use of two photon fluorescence as detection method of affinity binding reactions. We use a resonant grating waveguide structure as platform enhancement for detecting the interaction between fluorescent labeled Boldenone, a non-natural androgenic hormone, and a specific anti-anabolic antibody. We were able to detect a surface coverage of approximately 0.7 ng/mm(2).</description><subject>Androgens - analysis</subject><subject>Biological Assay - instrumentation</subject><subject>Biosensing Techniques - instrumentation</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Immunoassay - instrumentation</subject><subject>Microscopy, Fluorescence, Multiphoton - instrumentation</subject><subject>Nonlinear Dynamics</subject><subject>Photometry - instrumentation</subject><subject>Refractometry - instrumentation</subject><subject>Transducers</subject><issn>1094-4087</issn><issn>1094-4087</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkD1PwzAURS0EoqWwMSNPTKT4xY6TjAiVD6miC7BatmNDUGIXOx767zFqJZjufdLR1dNB6BLIEihnt5vVEviSAKVQHaE5kJYVjDT18b8-Q2cxfhECrG7rUzSDpgaoeDNH7y_eDb0zMuB-HJPzdkg-mKiNm7CMUe6w9QFL1wX_YVyv8acPo3cmYiWj6bB3OOPeyczHKSQ9pXyfoxMrh2guDrlAbw-r1_unYr15fL6_WxealvVUaFK1knOVE3RtAKTsFCedbrWyWrKGMkWBsYZX1DbMlLSxVgGUoHTJKqALdL3f3Qb_nUycxNjn34dBOuNTFLxlrMwWMnizB3XwMQZjxTb0oww7AUT8ehSblQAu9h4zfnXYTWo03R98EEd_AGAlb0E</recordid><startdate>20080818</startdate><enddate>20080818</enddate><creator>Thayil, Anisha</creator><creator>Muriano, Alejandro</creator><creator>Salvador, J-Pablo</creator><creator>Galve, Roger</creator><creator>Marco, Maria P</creator><creator>Zalvidea, Dobryna</creator><creator>Loza-Alvarez, Pablo</creator><creator>Katchalski, Tsvi</creator><creator>Grinvald, Eran</creator><creator>Friesem, Asher A</creator><creator>Soria, Silvia</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080818</creationdate><title>Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures</title><author>Thayil, Anisha ; Muriano, Alejandro ; Salvador, J-Pablo ; Galve, Roger ; Marco, Maria P ; Zalvidea, Dobryna ; Loza-Alvarez, Pablo ; Katchalski, Tsvi ; Grinvald, Eran ; Friesem, Asher A ; Soria, Silvia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c327t-c059a66bc051c7e11aadb60dc9cbfca4834b31448653f84e238ffb1121bc24513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Androgens - analysis</topic><topic>Biological Assay - instrumentation</topic><topic>Biosensing Techniques - instrumentation</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Immunoassay - instrumentation</topic><topic>Microscopy, Fluorescence, Multiphoton - instrumentation</topic><topic>Nonlinear Dynamics</topic><topic>Photometry - instrumentation</topic><topic>Refractometry - instrumentation</topic><topic>Transducers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thayil, Anisha</creatorcontrib><creatorcontrib>Muriano, Alejandro</creatorcontrib><creatorcontrib>Salvador, J-Pablo</creatorcontrib><creatorcontrib>Galve, Roger</creatorcontrib><creatorcontrib>Marco, Maria P</creatorcontrib><creatorcontrib>Zalvidea, Dobryna</creatorcontrib><creatorcontrib>Loza-Alvarez, Pablo</creatorcontrib><creatorcontrib>Katchalski, Tsvi</creatorcontrib><creatorcontrib>Grinvald, Eran</creatorcontrib><creatorcontrib>Friesem, Asher A</creatorcontrib><creatorcontrib>Soria, Silvia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Optics express</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thayil, Anisha</au><au>Muriano, Alejandro</au><au>Salvador, J-Pablo</au><au>Galve, Roger</au><au>Marco, Maria P</au><au>Zalvidea, Dobryna</au><au>Loza-Alvarez, Pablo</au><au>Katchalski, Tsvi</au><au>Grinvald, Eran</au><au>Friesem, Asher A</au><au>Soria, Silvia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures</atitle><jtitle>Optics express</jtitle><addtitle>Opt Express</addtitle><date>2008-08-18</date><risdate>2008</risdate><volume>16</volume><issue>17</issue><spage>13315</spage><epage>13322</epage><pages>13315-13322</pages><issn>1094-4087</issn><eissn>1094-4087</eissn><abstract>We report for the first time the use of two photon fluorescence as detection method of affinity binding reactions. We use a resonant grating waveguide structure as platform enhancement for detecting the interaction between fluorescent labeled Boldenone, a non-natural androgenic hormone, and a specific anti-anabolic antibody. We were able to detect a surface coverage of approximately 0.7 ng/mm(2).</abstract><cop>United States</cop><pmid>18711568</pmid><doi>10.1364/OE.16.013315</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1094-4087 |
| ispartof | Optics express, 2008-08, Vol.16 (17), p.13315-13322 |
| issn | 1094-4087 1094-4087 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69442094 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Androgens - analysis Biological Assay - instrumentation Biosensing Techniques - instrumentation Equipment Design Equipment Failure Analysis Immunoassay - instrumentation Microscopy, Fluorescence, Multiphoton - instrumentation Nonlinear Dynamics Photometry - instrumentation Refractometry - instrumentation Transducers |
| title | Nonlinear immunofluorescent assay for androgenic hormones based on resonant structures |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T22%3A07%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nonlinear%20immunofluorescent%20assay%20for%20androgenic%20hormones%20based%20on%20resonant%20structures&rft.jtitle=Optics%20express&rft.au=Thayil,%20Anisha&rft.date=2008-08-18&rft.volume=16&rft.issue=17&rft.spage=13315&rft.epage=13322&rft.pages=13315-13322&rft.issn=1094-4087&rft.eissn=1094-4087&rft_id=info:doi/10.1364/OE.16.013315&rft_dat=%3Cproquest_cross%3E69442094%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69442094&rft_id=info:pmid/18711568&rfr_iscdi=true |