Dual Effect of Anandamide on Rat Placenta Nitric Oxide Synthesis

Abstract Anandamide (AEA) has been reported to have pleiotropic effects on reproduction, but the mechanism by which it exerts these effects is unclear. The aim of this study is to characterize rat placental endocannabinoid system and to analyze the possible functional role of AEA in the regulation o...

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Veröffentlicht in:	Placenta (Eastbourne) 2008-08, Vol.29 (8), p.699-707
Hauptverfasser:	Cella, M, Leguizamón, G.F, Sordelli, M.S, Cervini, M, Guadagnoli, T, Ribeiro, M.L, Franchi, A.M, Farina, M.G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anandamide and TRPV1 Animals Arachidonic Acids - pharmacology Arachidonic Acids - physiology Biological and medical sciences Cannabinoid Receptor Modulators - metabolism Cannabinoid Receptor Modulators - pharmacology Embryology: invertebrates and vertebrates. Teratology Endocannabinoids Female Fundamental and applied biological sciences. Psychology Indomethacin - pharmacology Internal Medicine Nitric oxide Nitric Oxide - biosynthesis Nitric Oxide Synthase - metabolism Obstetrics and Gynecology Placenta Placenta - drug effects Placenta - metabolism Polyunsaturated Alkamides - pharmacology Pregnancy Rats Rats, Wistar Receptor, Cannabinoid, CB1 - metabolism Receptor, Cannabinoid, CB1 - physiology Receptor, Cannabinoid, CB2 - metabolism Receptor, Cannabinoid, CB2 - physiology Tocolytic Agents - pharmacology TRPV Cation Channels - metabolism
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