The Effects of Sildenafil Citrate on Ischemic Colonic Anastomotic Healing in Rats: Its Relationship Between Nitric Oxide and Oxidative Stress

Background The purpose of this study was to examine the effects of sildenafil citrate on normal and ischemic colon anastomosis in the rat model by measuring the levels of blood and colonic tissues nitric oxide, thiobarbituric acid reactive substrates (as a marker of lipid peroxidation), and glutathi...

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Veröffentlicht in:	World journal of surgery 2008-09, Vol.32 (9), p.2107-2113
Hauptverfasser:	Uzun, Hafize, Konukoglu, D., Nuri, M. K., Ersoy, E. Y., Özçevik, S., Yavuz, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Anastomosis, Surgical Anastomotic Healing Animals Biological and medical sciences Biomarkers - metabolism Cardiac Surgery Cerrahpasa Medical Faculty Colon - blood supply Colon - drug effects Colon - surgery Colonic Anastomotic Healing General aspects General Surgery Glutathione - metabolism Ischemia - drug therapy Male Medical sciences Medicine Medicine & Public Health Nitric Oxide - metabolism Oxidative Stress Piperazines - pharmacology Plasma TBARS Purines - pharmacology Rats Rats, Wistar Sildenafil Citrate Statistics, Nonparametric Sulfones - pharmacology Surgery TBARS Level Thiobarbituric Acid Reactive Substances - metabolism Thoracic Surgery Vascular Surgery Wound Healing - drug effects
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