Infants colonized with enterotoxin-producing staphylococci at 3 months display a decreased frequency of interferon-γ-producing CD45RO lymphocytes upon stimulation with staphylococcal enterotoxin A at birth but not at 6 months of age

The aim of the study was to elucidate the relationship between the cytokine response to staphylococcal enterotoxin A (SEA) at birth and subsequent staphylococcal colonization in the first months of life. In a cohort of 45 newborns, cord blood lymphocytes were stimulated with SEA (10 ng/ml) in vitro,...

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Veröffentlicht in:	Pediatric allergy and immunology 1999-11, Vol.10 (4), p.241-248
Hauptverfasser:	Schauer, Uwe, Thurau, Anja, Seitz, Miriam, Nowak, Lars, Petri, Holger, Leinhaas, Claudia, Rieger, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors antigens Bacterial diseases Biological and medical sciences CD45 immunology enterotoxins Enterotoxins - immunology Female Fetal Blood - immunology Human bacterial diseases Humans In Vitro Techniques Infant Infant, Newborn Infectious diseases interferon type II Interferon-gamma - biosynthesis interleukin-2 interleukin-4 Interleukin-4 - biosynthesis interleukin-5 Interleukin-5 - biosynthesis Leukocyte Common Antigens - metabolism Lymphocyte Activation Male Medical sciences Nose - microbiology Staphylococcal Infections - etiology Staphylococcal Infections - immunology Staphylococcal Infections - microbiology Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus aureus - immunology Staphylococcus aureus - isolation & purification Staphylococcus aureus - pathogenicity T-Lymphocyte Subsets - immunology
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