$Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure$

Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure

Abstract Several lines of evidence suggest that inflammatory processes mediated by cytokines are involved in the pathogenesis of heart failure (HF). However, the regulation of cytokine expression and the role of cytokines during HF development are not well understood. To address this issue, we have...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2008-08, Vol.45 (2), p.261-269
Hauptverfasser:	Husberg, Cathrine, Nygård, Ståle, Finsen, Alexandra Vanessa, Damås, Jan Kristian, Frigessi, Arnoldo, Øie, Erik, Wæhre, Anne, Gullestad, Lars, Aukrust, Pål, Yndestad, Arne, Christensen, Geir
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Cardiomyocytes Cardiovascular Cells, Cultured Chemokine CX3CL1 - biosynthesis Chemokine CX3CL1 - genetics Chemokine CX3CL1 - physiology CX3CL1 Cytokine Disease Models, Animal Down-Regulation - genetics Female Fractalkine Gene Expression Profiling Heart failure Heart Failure - metabolism Heart Failure - pathology Humans Inflammation Male Mice Mice, Inbred C57BL Microarray Middle Aged Myocardium - metabolism Myocardium - pathology Myocytes, Cardiac - metabolism Oligonucleotide Array Sequence Analysis Rats Rats, Wistar Up-Regulation - genetics
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