Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution
Bioactive peptides represent an exciting area of research in the fields of biochemistry and medicine and in particular the VIP/PACAP network appears to be of interest. Vasoactive intestinal peptide (VIP) is a pleiotropic factor that exerts a physiological regulatory influence and is involved in the...
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Veröffentlicht in: | Amino acids 2008-08, Vol.35 (2), p.275-281 |
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creator | Caraglia, M Carteni, M Dicitore, A Cassese, D De Maria, S Ferranti, P Giuberti, G Abbruzzese, A Stiuso, P |
description | Bioactive peptides represent an exciting area of research in the fields of biochemistry and medicine and in particular the VIP/PACAP network appears to be of interest. Vasoactive intestinal peptide (VIP) is a pleiotropic factor that exerts a physiological regulatory influence and is involved in the pathogenesis of several human disorders. In this paper we have reported structural characterization of VIP by experimental and computational methods as well as a comparative analysis of the peptide with its transglutaminase catalyzed analog VIP-Diaminopropane (VIP-DAP). |
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Vasoactive intestinal peptide (VIP) is a pleiotropic factor that exerts a physiological regulatory influence and is involved in the pathogenesis of several human disorders. In this paper we have reported structural characterization of VIP by experimental and computational methods as well as a comparative analysis of the peptide with its transglutaminase catalyzed analog VIP-Diaminopropane (VIP-DAP).</description><identifier>ISSN: 0939-4451</identifier><identifier>EISSN: 1438-2199</identifier><identifier>DOI: 10.1007/s00726-007-0567-3</identifier><identifier>PMID: 17619118</identifier><language>eng</language><publisher>Vienna: Vienna : Springer-Verlag</publisher><subject>Amino acids ; Analytical Chemistry ; Animals ; Biochemical Engineering ; Biochemistry ; Biomedical and Life Sciences ; Comparative analysis ; Computational study ; Diamines - chemistry ; Disorders ; Human ; Humans ; Life Sciences ; Limited proteolysis ; Mathematical models ; Models, Molecular ; Networks ; Neurobiology ; Pathogenesis ; Peptides ; Proteomics ; Review Article ; Solutions - chemistry ; Studies ; Time Factors ; Transglutaminase (TGase) ; Vasoactive intestinal peptide (VIP) ; Vasoactive Intestinal Peptide - chemistry ; VPAC receptors</subject><ispartof>Amino acids, 2008-08, Vol.35 (2), p.275-281</ispartof><rights>Springer-Verlag 2007</rights><rights>Springer-Verlag 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-f731e5e8fb09c42fd8c34a6a9e77fcc40298092b264fd937c6dfa82804e2ea7b3</citedby><cites>FETCH-LOGICAL-c458t-f731e5e8fb09c42fd8c34a6a9e77fcc40298092b264fd937c6dfa82804e2ea7b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00726-007-0567-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00726-007-0567-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17619118$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Caraglia, M</creatorcontrib><creatorcontrib>Carteni, M</creatorcontrib><creatorcontrib>Dicitore, A</creatorcontrib><creatorcontrib>Cassese, D</creatorcontrib><creatorcontrib>De Maria, S</creatorcontrib><creatorcontrib>Ferranti, P</creatorcontrib><creatorcontrib>Giuberti, G</creatorcontrib><creatorcontrib>Abbruzzese, A</creatorcontrib><creatorcontrib>Stiuso, P</creatorcontrib><title>Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution</title><title>Amino acids</title><addtitle>Amino Acids</addtitle><addtitle>Amino Acids</addtitle><description>Bioactive peptides represent an exciting area of research in the fields of biochemistry and medicine and in particular the VIP/PACAP network appears to be of interest. Vasoactive intestinal peptide (VIP) is a pleiotropic factor that exerts a physiological regulatory influence and is involved in the pathogenesis of several human disorders. In this paper we have reported structural characterization of VIP by experimental and computational methods as well as a comparative analysis of the peptide with its transglutaminase catalyzed analog VIP-Diaminopropane (VIP-DAP).</description><subject>Amino acids</subject><subject>Analytical Chemistry</subject><subject>Animals</subject><subject>Biochemical Engineering</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Comparative analysis</subject><subject>Computational study</subject><subject>Diamines - chemistry</subject><subject>Disorders</subject><subject>Human</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Limited proteolysis</subject><subject>Mathematical models</subject><subject>Models, Molecular</subject><subject>Networks</subject><subject>Neurobiology</subject><subject>Pathogenesis</subject><subject>Peptides</subject><subject>Proteomics</subject><subject>Review Article</subject><subject>Solutions - chemistry</subject><subject>Studies</subject><subject>Time Factors</subject><subject>Transglutaminase (TGase)</subject><subject>Vasoactive intestinal peptide (VIP)</subject><subject>Vasoactive Intestinal Peptide - 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subjects | Amino acids Analytical Chemistry Animals Biochemical Engineering Biochemistry Biomedical and Life Sciences Comparative analysis Computational study Diamines - chemistry Disorders Human Humans Life Sciences Limited proteolysis Mathematical models Models, Molecular Networks Neurobiology Pathogenesis Peptides Proteomics Review Article Solutions - chemistry Studies Time Factors Transglutaminase (TGase) Vasoactive intestinal peptide (VIP) Vasoactive Intestinal Peptide - chemistry VPAC receptors |
title | Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution |
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