Integrated GC-MS and LC-MS plasma metabonomics analysis of ankylosing spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that predominantly affects the axial skeleton in adolescent patients. The natural history of the disease remains poorly characterized. In this study, we combined GC-MS and LC-MS techniques to evaluate the major metabolic changes in the...

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Veröffentlicht in:	Analyst (London) 2008-09, Vol.133 (9), p.1214-1220
Hauptverfasser:	Gao, Peng, Lu, Chen, Zhang, Fengxia, Sang, Ping, Yang, Dawei, Li, Xiang, Kong, Hongwei, Yin, Peiyuan, Tian, Jing, Lu, Xin, Lu, Aiping, Xu, Guowang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analytical chemistry Blood Proteins - analysis Case-Control Studies Chemistry Child Child, Preschool Chromatographic methods and physical methods associated with chromatography Chromatography, Liquid - methods Discriminant Analysis Exact sciences and technology Gas chromatographic methods Gas Chromatography-Mass Spectrometry - methods Humans Male Mass Spectrometry - methods Metabolomics - methods Middle Aged Molecular Weight Pattern Recognition, Automated Sensitivity and Specificity Spectrometric and optical methods Spondylitis, Ankylosing - blood
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