Metabonomic profiling of renal cell carcinoma: High-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis

Metabonomic profiling using proton nuclear magnetic resonance ( 1H NMR) spectroscopy and multivariate data analysis of human serum samples was used to characterize metabolic profiles in renal cell carcinoma (RCC). We found distinct, easily detectable differences between (a) RCC patients and healthy...

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Veröffentlicht in:	Analytica chimica acta 2008-08, Vol.624 (2), p.269-277
Hauptverfasser:	Gao, Hongchang, Dong, Baijun, Liu, Xia, Xuan, Hanqing, Huang, Yiran, Lin, Donghai
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Biological and medical sciences Carcinoma Carcinoma, Renal Cell - blood Carcinoma, Renal Cell - diagnosis Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - surgery Case-Control Studies Chemistry Exact sciences and technology Humans Kidneys Magnetic Resonance Spectroscopy - methods Male Medical sciences Metabonomics Middle Aged Multivariate Analysis Nephrectomy Nephrology. Urinary tract diseases Pattern recognition Prognosis Proton nuclear magnetic resonance Protons Renal cell Spectrometric and optical methods Time Factors Tumors of the urinary system
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