Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals

Purpose For the development of a safe and effective dual inhibitor of anticancer drug efflux transporters P-glycoprotein and multidrug resistance protein 1 (MRP1) to conquer multidrug resistance, we investigated the effects of dietary phytochemicals on the functions of P-glycoprotein and MRP1. Metho...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer chemotherapy and pharmacology 2008-10, Vol.62 (5), p.867-873
Hauptverfasser:	Nabekura, Tomohiro, Yamaki, Takeshi, Ueno, Kazuyuki, Kitagawa, Shuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Antibiotics, Antineoplastic - metabolism Antibiotics, Antineoplastic - pharmacology Antineoplastic agents Antineoplastic Agents, Phytogenic - pharmacology ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors Biological and medical sciences Cancer Research Daunorubicin - metabolism Diet Doxorubicin - pharmacology Drug Resistance, Neoplasm Flavonoids - pharmacology Fluoresceins - metabolism Glycyrrhetinic Acid - pharmacology Humans KB Cells Medical sciences Medicine Medicine & Public Health Oncology Original Article Pharmacology. Drug treatments Pharmacology/Toxicology Plants - chemistry Vinblastine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!