Reduced expression of low-density lipoprotein receptor in hepatocellular carcinoma with paraneoplastic hypercholesterolemia

Background and Aim: Hepatocellular carcinoma (HCC) is frequently associated with paraneoplastic hypercholesterolemia. In familial hypercholesterolemia, genetic mutation of the low‐density lipoprotein (LDL) receptor gene has been recognized as being a pathogenesis of the disease. We investigate the...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2008-07, Vol.23 (7pt2), p.e153-e156
Hauptverfasser:	Sohda, Tetsuro, Iwata, Kaoru, Kitamura, Yuji, Suzuki, Norihisa, Takeyama, Yasuaki, Irie, Makoto, Anan, Akira, Nakane, Hidetoshi, Yoshikane, Makoto, Watanabe, Hiroshi, Sakisaka, Shotaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma, Hepatocellular - chemistry Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology chromosome 19p13.2 Chromosomes, Human, Pair 19 Chromosomes, Human, Pair 5 Down-Regulation Female Gene Expression Regulation, Neoplastic hepatocellular carcinoma Humans hypercholesterolemia Hypercholesterolemia - genetics Hypercholesterolemia - metabolism Hypercholesterolemia - pathology Immunohistochemistry Liver Neoplasms - chemistry Liver Neoplasms - genetics Liver Neoplasms - pathology Loss of Heterozygosity low-density lipoprotein receptor Male Middle Aged paraneoplastic syndrome Paraneoplastic Syndromes - genetics Paraneoplastic Syndromes - metabolism Paraneoplastic Syndromes - pathology Polymerase Chain Reaction Receptors, LDL - analysis Receptors, LDL - genetics
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