Early immune response in susceptible and resistant mice strains with chronic Pseudomonas aeruginosa lung infection determines the type of T-helper cell response

Most cystic fibrosis (CF) patients become chronically infected with Pseudomonas aeruginosa in the lungs. The infection is characterized by a pronounced antibody response and a persistant inflammation dominated by polymorphonuclear neutrophils. Moreover a high antibody response correlates with a poor...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 1999-12, Vol.107 (7-12), p.1093-1100
Hauptverfasser:	Moser, Claus, Hougen, Hans Petter, Song, Zhijun, Rygaard, JøRgen, Kharazmi, Arsalan, HøIby, Niels
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Bacterial diseases Bacteriology Biological and medical sciences Chronic Disease cystic fibrosis Cystic Fibrosis - complications Cytokines - biosynthesis Experimental bacterial diseases and models Female Fundamental and applied biological sciences. Psychology Humans Immunoglobulin G - blood Immunoglobulin G - classification In Vitro Techniques Infectious diseases lung infection Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C3H Microbiology mouse Nitric Oxide - biosynthesis Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pneumonia, Bacterial - complications Pneumonia, Bacterial - immunology Prognosis Pseudomonas aeruginosa Pseudomonas Infections - complications Pseudomonas Infections - immunology Species Specificity T-helper cell T-Lymphocytes, Helper-Inducer - immunology Th1 Cells - immunology Th1/Th2 Th2 Cells - immunology
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