Humoral Autoimmune Responses to the Squamous Cell Carcinoma Antigen Protein Family in Psoriasis

Substantial evidence indicates that psoriasis is a T-lymphocyte-mediated autoimmune disease. However, longstanding data also indicate IgG and complement deposition in upper epidermis of psoriasis plaques. This led us to propose that autoantigen–autoantibody interactions in the skin may also be of pa...

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Veröffentlicht in:	Journal of investigative dermatology 2008-09, Vol.128 (9), p.2219-2224
Hauptverfasser:	El-Rachkidy, Rana G., Young, Helen S., Griffiths, Christopher E.M., Camp, Richard D.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, Neoplasm - immunology Arginase Arginase - immunology Atopic dermatitis Autoantibodies Autoantibodies - immunology Autoantibodies - metabolism Autoantigens Autoantigens - immunology Autoimmune diseases Autoimmunity Biological and medical sciences Blood levels Case-Control Studies Data processing Dermatology Desorption Epidermis Epidermis - immunology Epidermis - metabolism Epidermis - pathology Female Humans Immunoblotting Immunoglobulin G Immunoglobulin G - immunology Immunoglobulin G - metabolism Internet Keratin Keratin-10 - immunology Lasers Male Mass spectroscopy Medical sciences Middle Aged Phosphopyruvate hydratase Phosphopyruvate Hydratase - immunology Plaques protein families Psoriasis Psoriasis - immunology Psoriasis - metabolism Psoriasis - pathology Psoriasis. Parapsoriasis. Lichen serpins Serpins - immunology Skin squamous cell carcinoma Tryptic peptides
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