Control of Muscle Cell-Type Specification in the Zebrafish Embryo by Hedgehog Signalling

The specification of different muscle cell types in the zebrafish embryo requires signals that emanate from the axial mesoderm. In previous studies we and others have shown that overexpression of different members of the Hedgehog protein family can induce the differentiation of two types of slow-twi...

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Veröffentlicht in:	Developmental biology 1999-12, Vol.216 (2), p.469-480
Hauptverfasser:	Lewis, K.E, Currie, P.D, Roy, S, Schauerte, H, Haffter, P, Ingham, P.W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation chameleon Fluorescent Antibody Technique Gene Expression Regulation, Developmental Gli2 Hedgehog Proteins In Situ Hybridization Kruppel-Like Transcription Factors Membrane Proteins - genetics muscle fibre type Muscles - embryology Muscles - metabolism Mutation myoD MyoD Protein - genetics myosin heavy chain Myosins - metabolism Patched Receptors Patched-1 Receptor Patched1 Proteins - metabolism Receptors, Cell Surface RNA, Messenger - metabolism Signal Transduction Somites - metabolism Sonic hedgehog sonic you Trans-Activators Transcription Factors - metabolism u-boot u-type mutants you you-too Zebrafish Zebrafish Proteins Zinc Finger Protein Gli2
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