Growth factors reduce the suppression of proliferation and osteogenic differentiation by titanium particles on MSCs

This study was conducted to test the hypothesis that growth factors can reduce the suppressive effect of titanium particles on MSCs. Cultured human MSCs at passage 3 were challenged with prepared cpTi particles at a concentration of 500 particles/cell along with one of the following growth factors:...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2008-09, Vol.86A (4), p.1137-1144
Hauptverfasser:	Jeong, Woong-Kyo, Park, Sang-Won, Im, Gun-Il
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism arthroplasty Blotting, Western Cell Differentiation - drug effects Cell Proliferation - drug effects Cell Survival - drug effects growth factor Humans Intercellular Signaling Peptides and Proteins - pharmacology mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - enzymology Osteogenesis - drug effects Osteogenesis - genetics periprosthetic osteolysis Reverse Transcriptase Polymerase Chain Reaction titanium Titanium - pharmacology
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