The Chemokine Receptor Cxcr3 Is Not Essential for Acute Cardiac Allograft Rejection in Mice and Rats

Chemokine receptors have gained attention as potential targets for novel therapeutic strategies. We investigated the mechanisms of allograft rejection in chemokine receptor Cxcr3‐deficient mice using a model of acute heart allograft rejection in the strain combination BALB/c to C57BL/6. Allograft su...

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Veröffentlicht in:	American journal of transplantation 2008-08, Vol.8 (8), p.1604-1613
Hauptverfasser:	Zerwes, H.‐G., Li, J., Kovarik, J., Streiff, M., Hofmann, M., Roth, L., Luyten, M., Pally, C., Loewe, R. P., Wieczorek, G., Bänteli, R., Thoma, G., Luckow, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chemokine Cxcr3 Cyclosporine - administration & dosage gene expression profiling Graft Rejection Graft Survival Heart Transplantation - immunology Medical sciences Mice Mice, Inbred C57BL Rats receptors Receptors, CXCR3 - metabolism Reverse Transcriptase Polymerase Chain Reaction Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Transplantation, Homologous
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