A new form of Filgrastim with sustained duration in vivo and enhanced ability to mobilize PBPC in both mice and humans

Granulocyte colony-stimulating factor (G-CSF) has proven effective in the prophylaxis of chemotherapy-induced neutropenia and as a mobilizer of peripheral blood progenitor cells. The longevity of G-CSF action is limited by its removal from the body by two mechanisms. The first is thought to be media...

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Veröffentlicht in:	Experimental hematology 1999-12, Vol.27 (12), p.1724-1734
Hauptverfasser:	Molineux, Graham, Kinstler, Olaf, Briddell, Bob, Hartley, Cynthia, McElroy, Patricia, Kerzic, Patrick, Sutherland, Weston, Stoney, Greg, Kern, Brent, Fletcher, Frederick A., Cohen, Art, Korach, Elliot, Ulich, Tom, McNiece, Ian, Lockbaum, Pamela, Miller-Messana, Mary Ann, Gardner, Sheila, Hunt, Thomas, Schwab, Gisela
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Filgrastim Filgrastim SD/01 Granulocyte Colony-Stimulating Factor - analogs & derivatives Granulocyte Colony-Stimulating Factor - pharmacology Hematopoietic Stem Cell Mobilization Humans Mice Neutropenia PBPC mobilization Recombinant Proteins
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